52517

1,1,1,3,3,3-Hexafluoro-2-propanol

for GC derivatization, LiChropur^™, ≥99.8%

• Sinónimos: HFP, Hexafluoroisopropanol
• Fórmula lineal: (CF₃)₂CHOH
• Número de CAS: 920-66-1
• Peso molecular: 168.04
• Beilstein/REAXYS Number: 1841007
• EC Number: 213-059-4
• MDL number: MFCD00011651
• UNSPSC Code: 12352104
• PubChem Substance ID: 329757847
• NACRES: NA.05

Propiedades

• grade: for GC derivatization
• Quality Level: 100
• assay: ≥99.8% (GC); ≥99.8%
• quality: LiChropur^™
• reaction suitability: reagent type: derivatization reagent; reaction type: Acylations; reagent type: derivatization reagent; reaction type: Esterifications
• technique(s): gas chromatography (GC): suitable
• refractive index: n20/D 1.275 (lit.)
• bp: 59 °C (lit.)
• mp: −4 °C (lit.)
• density: 1.596 g/mL at 25 °C (lit.)
• SMILES string: OC(C(F)(F)F)C(F)(F)F
• InChI: 1S/C3H2F6O/c4-2(5,6)1(10)3(7,8)9/h1,10H
• InChI key: BYEAHWXPCBROCE-UHFFFAOYSA-N

Descripción

General description

Hexafluoroisopropanol (HFP) is generally used to denature the native state of proteins, and it also stabilizes the a-helical conformation in unfolded peptides and proteins like ß-lactoglobulin and melittin.

Application

Suitable for the derivatization of glutamic acid, homovanillic, iso-homovanillic and dihydroxyphenyl acetic acids and Υ-aminobutyric acid.

Other Notes

Reagent for hexafluoroisopropyl ester, N-pentafluoropropionyl, and trifluoroacetyl..

Size-exclusion chromatography in 1,1,1,3,3,3-hexafluoro-2-propanol

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• pictograms: GHS08,GHS05
• signalword: Danger
• hcodes: H314,H361,H373
• pcodes: P202 - P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Eye Dam. 1 - Repr. 2 - Skin Corr. 1A - STOT RE 2
• Storage Class: 8A - Combustible corrosive hazardous materials
• wgk_germany: WGK 2
• flash_point_f: No data available
• flash_point_c: No data available
• ppe: Faceshields, Gloves, Goggles