11271164001
Roche
Interleukin-2, mouse (mIL-2)
recombinant (E. coli)
Sinónimos:
mIL-2, mouse interleukin-2
About This Item
Productos recomendados
biological source
mouse
Quality Level
recombinant
expressed in E. coli
assay
>95% (SDS-PAGE)
form
solution
potency
<0.5 ng/mL EC50
mol wt
17,200 Da
packaging
pkg of 10,000 U (5 μg, 1 ml)
manufacturer/tradename
Roche
storage condition
avoid repeated freeze/thaw cycles
technique(s)
inhibition assay: suitable
impurities
<0.1 EU/μgtested (LAL test)
UniProt accession no.
storage temp.
−20°C
Gene Information
mouse ... Il2(16183)
General description
Specificity
Application
- Supports the growth of murine CTLL cells (murine T cell line), but not that of human T-cells.
- Strongly inhibits the binding of recombinant human IL-2 to murine responder cells.
- Weakly inhibits the binding to human responder cells.
- Shares identical biological and immunological activities with human IL-2.
- Is a convenient tool for extensive studies of the pharmacological and physiological activities of IL-2 in murine models.
- used for the stimulation of murine T-cells
Quality
Sequence
Unit Definition
Preparation Note
Storage conditions (working solution): -15 to -25 °C
Note: Avoid repeated freezing and thawing.
Other Notes
Note: The biological activity of this product may vary in different in vitro applications. Determine the optimal concentration range for specific applications.
EC 50 definition/Unit definition: The amount of mIL-2 that is required to support half-maximal stimulation of cell proliferation (XTT cleavage) with CTLL-2 cells (1 unit equals =0.5 ng).
Storage Class
12 - Non Combustible Liquids
wgk_germany
nwg
flash_point_f
No data available
flash_point_c
No data available
Certificados de análisis (COA)
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