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MAB427

Sigma-Aldrich

Anti-Dihydropyridine-sensitive Calcium Channel α 1 Subunit Antibody, clone 1a

ascites fluid, clone mAB 1a, Chemicon®

Sinónimos:

Anti-CACNL1A3, Anti-CCHL1A3, Anti-Cav1.1, Anti-HOKPP, Anti-HOKPP1, Anti-MHS5, Anti-TTPP1, Anti-hypoPP

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

100

antibody form

ascites fluid

antibody product type

primary antibodies

clone

mAB 1a, monoclonal

species reactivity

rabbit, mouse, human, rat

manufacturer/tradename

Chemicon®

technique(s)

flow cytometry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG1

NCBI accession no.

NM_000069.2

UniProt accession no.

Q13698

shipped in

dry ice

target post-translational modification

unmodified

Specificity

Dihydropyridine calcium channel, a1 subunit as determined by Western blot (~210 kDa), immunoprecipitation and functional test. Membrane preparations are recommended. The mouse muscle cell line, BC3H1 functions as a good positive control cell line. Reactive with L-type calcium channel alpha1 subunit. Specific for small cell carcinoma and neuroblastoma by FACS analysis. No interaction with squamous cell carcinoma or with cardiac calcium chanel isoforms.

Application

Anti-Dihydropyridine-sensitive Calcium Channel α 1 Subunit Antibody, clone 1a is an antibody against Dihydropyridine-sensitive Calcium Channel α 1 Subunit for use in FC, IP & WB.
Western blot, immunoprecipitation and FACS.

Optimal working dilutions must be determined by end user.

Linkage

Replaces: 06-422

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Isoform switching in myofibrillar and excitation-contraction coupling proteins contributes to diminished contractile function in regenerating rat soleus muscle.
Esposito, A; Germinario, E; Zanin, M; Palade, PT; Betto, R; Danieli-Betto, D
Journal of Applied Physiology (1985)
Monoclonal antibody to the alpha 1-subunit of the dihydropyridine-binding complex inhibits calcium currents in BC3H1 myocytes.
Morton, M E, et al.
The Journal of Biological Chemistry, 263, 613-616 (1988)
R G Parton et al.
The Journal of cell biology, 136(1), 137-154 (1997-01-13)
Caveolae, flask-shaped invaginations of the plasma membrane, are particularly abundant in muscle cells. We have recently cloned a muscle-specific caveolin, termed caveolin-3, which is expressed in differentiated muscle cells. Specific antibodies to caveolin-3 were generated and used to characterize the
Localization of Cacna1s to ON bipolar dendritic tips requires mGluR6-related cascade elements.
Tummala, SR; Neinstein, A; Fina, ME; Dhingra, A; Vardi, N
Investigative Ophthalmology & Visual Science null
Calcium channels are involved in calcium oxalate crystal formation in specialized cells of Pistia stratiotes L.
Volk, GM; Goss, LJ; Franceschi, VR
Annals of Botany null
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