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Merck
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Key Documents

8.55007

Sigma-Aldrich

NovaSyn®TG amino resin (90 µm)

Novabiochem®

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About This Item

UNSPSC Code:
13111023
NACRES:
NA.22

Quality Level

200

product line

NovaSyn® TG
Novabiochem®

form

beads

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

functional group

amine

storage temp.

2-30°C

General description

NovaSyn TG resin is a composite of polyethylene glycol and a low-crosslinked polystyrene gel-type resin [1,2,3]. The 90 μm beads have a narrow size distribution, excellent pressure stability and swelling properties, and high diffusion rates, making them ideally suited for both batch or continuous flow peptide synthesis. Functionalized with an amino group, the resin can be readily derivatized with any carboxylic acid-containing linker using standard methods of amide bond formation. Furthermore, the excellent swelling properties in water of this support make it well suited to the preparation of peptide libraries.

Associated Protocols and Technical Articles

Protocols for Loading of Peptide Synthesis Resins

Literature references

[1] W. Rapp, et al. in ′Innovation & Perspectives in Solid Phase Synthesis, 1st International Symposium′, R. Epton (Eds), SPCC UK Ltd., Birmingham, 1990, pp. 205.
[2] L. Zhang, et al. in ′Peptides 1990, Proc. 21st European Peptide Symposium′, E. Giralt & D. Andreu (Eds), ESCOM, Leiden, 1990, pp.196.
[3] E. Bayer (1991) Angew. Chem. Int. Ed. Engl., 30, 113.

Linkage

Replaces: 01-64-0043

Analysis Note

Color (visual): white to yellow to beige
Appearance of substance (visual): beads
Loading (determined from the substitution of the Fmoc-Leu loaded resin): 0.20 - 0.30 mmol/g
Swelling Volume (in CH₂Cl₂): lot specific result
The base resin ist PEG-PS copolymer (90µm), functionalised with an amino group.

Legal Information

NOVASYN is a registered trademark of Merck KGaA, Darmstadt, Germany
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Contenido relacionado

Base Resins for Peptide Synthesis

The Novabiochem® product line has one of the most extensive ranges of polymer-supports for solid phase peptide synthesis. They range from high-loaded, lows welling for the large-scale production of relatively short peptides to high-swelling, low-loaded for the synthesis of long or difficult sequences.

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

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