454428

4-Methylumbelliferyl-6-sulfo-N-acetyl-β-D-glucosaminide, Potassium Salt

Fluorogenic substrate for isoenzyme A of N-acetyl-β-D-glucosaminidase (hexosaminidase A). Can be used for the prenatal diagnosis of Tay-Sachs disease and for the classification of GM2 gangliosidosis genotypes.

• Sinónimos: 4-Methylumbelliferyl-6-sulfo-N-acetyl-β-D-glucosaminide, Potassium Salt, 4-Methylumbelliferyl-6-sulfo-2-acetamido-2-deoxy-β-D-glucopyranoside, K
• Fórmula empírica (notación de Hill): C₁₈H₂₀NO₁₁S · K
• Peso molecular: 497.51
• UNSPSC Code: 12352200

Propiedades

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: crystalline solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; desiccated; protect from light
• color: white
• solubility: water: 20 mg/mL
• fluorescence: λ_ex 360 nm; λ_em 440 nm
• shipped in: ambient
• storage temp.: −20°C

Descripción

General description

Fluorogenic substrate for isoenzyme A of N-acetyl-β-D-glucosaminidase (hexosaminidase A). Can be used for the prenatal diagnosis of Tay-Sachs disease and for the classification of GM₂ gangliosidosis genotypes.

Fluorogenic substrate for isoenzyme A of N-acetyl-β-D-glucosaminidase (hexosaminidase A). Can be used for the prenatal diagnosis of Tay-Sachs disease and for the classification of GM₂ gangliosidosis genotypes. Excitation maximum: ~360 nm; emission maximum: ~440 nm.

Warning

Toxicity: Standard Handling (A)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.

Other Notes

Greloner, E.E., and Wenger, D.A. 1987. Prenat. Diag. 7, 419.
Bayleran, J., et al. 1984. Clin. Chim. Acta143, 73.
Inui, K., and Wenger, D.A. 1984. Clin. Genet.25, 93.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable