220411

Chenodeoxycholic Acid, Sodium Salt

Bile acid that has been shown to increase intracellular Ca2+ in isolated rat hepatocyte couplets. Induces a permeability transition in freshly isolated rat liver mitochondria.

• Sinónimos: Chenodeoxycholic Acid, Sodium Salt
• Fórmula empírica (notación de Hill): C₂₄H₃₉O₄ · Na
• Número de CAS: 2646-38-0
• Peso molecular: 414.55
• MDL number: MFCD00065452
• UNSPSC Code: 12161902
• NACRES: NA.21

Propiedades

• Quality Level: 100
• assay: >95% (TLC)
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; desiccated (hygroscopic)
• color: white
• solubility: water: 20 mg/mL; aqueous buffer: soluble
• cation traces: heavy metals: <10 ppm
• shipped in: ambient
• storage temp.: 15-25°C
• InChI: 1S/C24H40O4.Na/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10-8-16(25)12-15(23)13-20(22)26;/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28);/q;+1/p-1/t14-,15+,16-,17-,18+,19+,20-,22+,23+,24-;/m1./s1
• InChI key: WDFRNBJHDMUMBL-OICFXQLMSA-M

Descripción

General description

Bile acid that has been shown to increase intracellular Ca²⁺ in isolated rat hepatocyte couplets.

Bile acid that has been shown to increase intracellular Ca²⁺ in isolated rat hepatocyte couplets. Induces a permeability transition in freshly isolated rat liver mitochondria.

Warning

Toxicity: Harmful & Carcinogenic / Teratogenic (E)

Other Notes

Rolo, A.P., et al. 2001. Biosci. Rep.21, 73.
Thibault, N., and Ballet, F. 1993. Biochem. Pharmacol. 45, 289.
Roda, A., et al. 1990. J. Lipid Res.31, 1433.
Spivak, W., et al. 1988. Biochem. J.252, 275.
Hisadome, T., et al. 1980. Gastroenterol. Jpn.15, 257.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• pictograms: GHS06,GHS08
• signalword: Danger
• hcodes: H301,H361d
• pcodes: P202 - P264 - P270 - P280 - P301 + P310 - P405
• Hazard Classifications: Acute Tox. 3 Oral - Repr. 2
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable