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14-573-M

Sigma-Aldrich

Pim1 Protein, active, 10 µg

Active, N-terminal GST-tagged recombinant human full length Pim-1, for use in Kinase Assays.

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About This Item

UNSPSC Code:
12352202
eCl@ss:
32160405
NACRES:
NA.32

biological source

human

Quality Level

recombinant

expressed in E. coli

mol wt

Mw 62 kDa

manufacturer/tradename

Upstate®

technique(s)

activity assay: suitable (kinase)

NCBI accession no.

UniProt accession no.

General description

N-terminal GST-tagged recombinant human full length Pim-1
Product Source: expressed in E. coli cells

Application

Research Category
Inflammation & Immunology

Biochem/physiol Actions

Protein Target: Pim-1
Target Sub-Family: CAMK

Packaging

Also available in 250 µg size --call for pricing and availability and reference catalog number 14-573M when ordering the 250 µg size.

Quality

routinely evaluated by phosphorylation of S6 Kinase/Rsk-2 Substrate Peptide 2

Physical form

Glutathione agarose affinity chromatography

Storage and Stability

6 months at -70°C

Other Notes

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Skin Sens. 1

Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Miriam López-Ramos et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 24(9), 3171-3185 (2010-04-20)
Protein kinase casein kinase 2 (CK2) is a serine/threonine kinase with evidence of implication in growth dysregulation and apoptosis resistance, making it a relevant target for cancer therapy. Several CK2 inhibitors have been developed showing variable efficiency, emphasizing the need

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