1.16129

LiChrospher^® 100 RP-8 (5 µm) HPLC Columns

HPLC sorbent

• Sinónimos: TM=["LiChrospher"] C8 sorbent for HPLC
• UNSPSC Code: 41115709
• NACRES: SB.52

Propiedades

• product name: LiChrospher^® 100 RP-8 (5 µm),
• material: stainless steel column
• agency: suitable for USP L7
• product line: LiChrospher^®
• feature: endcapped: no
• extent of labeling: 12.5% Carbon loading
• parameter: 60 °C max. temp.
• technique(s): HPLC: suitable; mass spectrometry (MS): suitable (Low - Medium)
• surface area: 350 m²/g
• matrix: fully porous particle
• matrix active group: C8 bonding phase
• particle size: 5 μm
• pore size: 100 Å pore size
• operating pH range: 2-7.5
• bulk density: 200‑400 kg/m³
• separation technique: reversed phase
• storage temp.: no temp limit

Descripción

General description

LiChrospher^® RP-8 is a reliable and versatile traditionally produced spherical silica gel carrier with C-8 reversed phase properties. It is well suited for the separation of neutral, acidic and weak basic compounds.

Application

• Development and validation of a HPLC-UV method for the determination in didanosine tablets.: This study presents a validated HPLC-UV method optimized using LiChrospher^® 100 RP-8 (5 µm) for analyzing didanosine in tablet formulations, offering a reliable tool for quality control in pharmaceutical environments (de Oliveira et al., 2005).


• Determination of steroid hormones in oral contraceptives by high-performance liquid chromatography.: Utilizes LiChrospher^® 100 RP-8 (5 µm) to effectively separate and quantify steroid hormones in oral contraceptive pills, demonstrating the column′s applicability in complex pharmaceutical analyses (Inês et al., 2002).


• Determination of fluoroquinolone residues in animal tissues by liquid chromatography.: Explores the use of LiChrospher^® 100 RP-8 (5 µm) for the sensitive detection of fluoroquinolone residues in animal tissues, highlighting its potential for food safety and veterinary medicine applications (Posyniak et al., 1999).


• Rapid and simple determination of oxytetracycline in chicken products.: Demonstrates the column′s efficiency in rapidly quantifying oxytetracycline residues in chicken, ensuring compliance with food safety standards (Furusawa, 1999).


• Crocheted ETFE-reactor for on-line post-column photoderivatization of diclofenac in high-performance liquid chromatography.: Describes an innovative application involving LiChrospher^® 100 RP-8 (5 µm) in a post-column reactor setup to enhance the detection sensitivity of diclofenac, underlining the column′s versatility in advanced analytical techniques (Kuhlmann et al., 1997).

Analysis Note

Application test: passes test
Pressure: ≤ 45 bar
Theoretical Plates (N/m) (Toluene): ≥ 60000
Capacity factor (Toluene): ≥ 0.7
stability testing (performance): passes test
separation factor (PTH-Lysine/PHB-Propyl-Ester, selectivity test): 1.20 - 1.55
separation factor (Naphthalene/Digitoxigenin, selectivity test): 3.5 - 4.7
separation factor (PTH-Lysine/Digitoxigenin, selsctivity test): 1.70 - 2.25
Particle Size (d10): 4.8 - 5.5 µm
Particle Size (d50): 6.5 - 7.5 µm
Particle Size (d90): 9.0 - 10.5 µm

Legal Information

LiChrospher is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: nwg
• flash_point_f: Not applicable
• flash_point_c: Not applicable