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Merck
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Key Documents

09-278

Sigma-Aldrich

Anti-20S proteasome subunit β5 Antibody

serum, Upstate®

Sinónimos:

LMP17, MB1

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.77

biological source

rabbit

Quality Level

100

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human

manufacturer/tradename

Upstate®

technique(s)

immunohistochemistry: suitable
western blot: suitable

isotype

IgG

NCBI accession no.

NM_002797.2

UniProt accession no.

P28074

shipped in

dry ice

Gene Information

human ... PSMB5(5693)

Specificity

Recognizes proteasome subunit β5

Immunogen

Peptide corresponding to residues 194-207 of human proteasome subunit β5 conjugated to KLH.

Application

Research Category
Protein Trafficking
Research Sub Category
Ubiquitin & Ubiquitin Metabolism
This Anti-20S proteasome subunit β5 Antibody is validated for use in IH, WB for the detection of 20S proteasome subunit β5.

Target description

22 kDa

Physical form

100 µL of purified antiserum preparation in PBS containing 0.09% sodium azide. Dilute to working strength with phosphate buffered saline pH 7.2-7.4.
antiserum

Storage and Stability

Stable for 1 year at -20°C from date of shipment for up to 12 months.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Cyriel S Olie et al.
iScience, 12, 318-332 (2019-02-11)
Reduced poly(A)-binding protein nuclear 1 (PABPN1) levels cause aging-associated muscle wasting. PABPN1 is a multifunctional regulator of mRNA processing. To elucidate the molecular mechanisms causing PABPN1-mediated muscle wasting, we compared the transcriptome with the proteome in mouse muscles expressing short
Muhammad Riaz et al.
PLoS genetics, 12(5), e1006031-e1006031 (2016-05-07)
Poly(A) Binding Protein Nuclear 1 (PABPN1) is a multifunctional regulator of mRNA processing, and its expression levels specifically decline in aging muscles. An expansion mutation in PABPN1 is the genetic cause of oculopharyngeal muscle dystrophy (OPMD), a late onset and
K Tanaka et al.
Molecular biology reports, 24(1-2), 3-11 (1997-03-01)
The 26S proteasome is an eukaryotic ATP-dependent, dumbbell-shaped protease complex with a molecular mass of approximately 2000 kDa. It consists of a central 20S proteasome, functioning as a catalytic machine, and two large V-shaped terminal modules, having possible regulatory roles

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