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Merck

H-107

Supelco

1,25-Dihydroxyvitamin D3-13C3 (25,26,27-13C3) solution

5 μg/mL in ethanol, ampule of 1 mL, certified reference material, Cerilliant®

Sinónimos:

Deuterated 1

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About This Item

Fórmula empírica (notación de Hill):
13C3C24H44O3
Peso molecular:
419.61
EC Number:
UNSPSC Code:
41116107
NACRES:
NA.24

grade

certified reference material

Quality Level

form

liquid

feature

(Snap-N-Spike®)

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

5 μg/mL in ethanol

mp

-143.99 °C

application(s)

clinical testing
clinical testing

format

single component solution

storage temp.

−70°C

SMILES string

O[C@@H](C[C@H](O)C/1=C)CC1=C\C=C2[C@@](CC[C@]3([H])[C@H](C)CCC[13C](O)([13CH3])[13CH3])([H])[C@]3(C)CCC\2

InChI

1S/C27H44O3/c1-18(8-6-14-26(3,4)30)23-12-13-24-20(9-7-15-27(23,24)5)10-11-21-16-22(28)17-25(29)19(21)2/h10-11,18,22-25,28-30H,2,6-9,12-17H2,1,3-5H3/b20-10+,21-11-/t18-,22-,23-,24+,25+,27-/m1/s1/i3+1,4+1,26+1

InChI key

GMRQFYUYWCNGIN-SYUIRNBGSA-N

General description

A stable-labeled internal standard suitable for quantitation of 1,25-Dihydroxyvitamin D3 levels by LC-MS/MS. 1,25-Dihydroxyvitamin D3, also known as calcitriol, is a hormonally active metabolite of vitamin D responsible for regulating calcium. Measurement of 1,25-Dihydroxyvitamin D3 is used to distinguish some cases of primary hyperparathyroidism from hypercalcemia of cancer and for the differential diagnosis of vitamin D-dependent rickets.

Application


  • Leigh Syndrome with HIBCH Mutations: Discusses the metabolic effects of mutations related to Leigh syndrome and includes information on 3-hydroxybutyryl carnitine isomers (Wang et al., 2021, frontiersin.org).

  • Highly Efficient Ketone Body Treatment in Leukodystrophy: Highlights the therapeutic potential of L-carnitine in treatments, specifically focusing on the metabolism of L-3-hydroxybutyryl-CoA in the context of fatty acid β-oxidation disorders (Gautschi et al., 2015, nature.com).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

related product

Referencia del producto
Descripción
Precios

pictograms

FlameExclamation mark

signalword

Danger

hcodes

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2

Storage Class

3 - Flammable liquids

wgk_germany

WGK 1

flash_point_f

57.2 °F - closed cup

flash_point_c

14.0 °C - closed cup


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