Saltar al contenido
Merck
Todas las fotos(1)

Key Documents

View All Documentation

LM4103

Avanti

7α-hydroxycholesterol (D7)

Avanti Research™ - A Croda Brand LM4103, methanol solution

Sinónimos:

cholest-5-en-3β,7α-diol(d7)

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
Todas las fotos(1)

About This Item

Fórmula empírica (notación de Hill):
C27H39D7O2
Número de CAS:
349553-94-2
Peso molecular:
409.70
UNSPSC Code:
12352100
NACRES:
NA.25

form

methanol solution

packaging

pkg of 1 × 1 mL (LM4103-1EA)

manufacturer/tradename

Avanti Research™ - A Croda Brand LM4103

concentration

~10 μg/mL (Refer to C of A for lot specific concentration. )

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@]12[C@]([C@](CC[C@H](O)C3)(C)C3=C[C@H]2O)([H])CC[C@@]4(C)[C@@]1([H])CC[C@]4([H])[C@]([H])(C)CCCC([2H])(C([2H])([2H])[2H])C([2H])([2H])[2H]

General description

7α-hydroxycholesterol is an oxysterol synthesized by the oxidation of the side chain of cholesterol. It is the precursor of bile acid.

Application

7α-hydroxycholesterol (D7) may be used:
  • as a deuterated sterol standard for the extraction of lipids from cultured cells
  • in liquid chromatography-high-resolution mass spectrometry method (LC-MS/HR-MS) for the quantification
  • to synthesize d4-7 -hydroxy-3-oxo-4-cholestenoic acid (d4-7-HOCA)

Packaging

2 mL Amber Glass Sealed Ampule (LM4103-1EA)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes

Storage Class

3 - Flammable liquids

wgk_germany

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Quantification of the 15 major human bile acids and their precursor 7? -hydroxy-4-cholesten-3-one in serum by liquid chromatography--tandem mass spectrometry
Steiner C, et al.
Journal of Chromatography. B, Biomedical Applications, 878(28), 2870-2880 (2010)
Oxysterols in the pathogenesis of major chronic diseases
Poli G, et al.
Redox Biology, 1(1), 125-130 (2013)
7 ? -hydroxy-3-oxo-4-cholestenoic acid in cerebrospinal fluid reflects the integrity of the blood-brain barrier
Saeed A, et al.
Journal of Lipid Research, 55(2), 313-318 (2014)
Extraction and analysis of sterols in biological matrices by high performance liquid chromatography electrospray ionization mass spectrometry
McDonald J, et al.
Test, 432, 145-170 (2007)
Zoltán Pataj et al.
Journal of chromatography. A, 1439, 82-88 (2015-11-27)
Oxysterols are important intermediates in numerous metabolic and catabolic pathways and their biological significance is also proven. The present paper describes a reliable and short liquid chromatography-high-resolution mass spectrometry method (LC-MS/HR-MS) for the quantification of 8 different oxysterols (24(S)-hydroxycholesterol, 25-hydroxycholesterol

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico