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LM1202

Avanti

17:0-20:4 PG

Avanti Research™ - A Croda Brand

Sinónimos:

1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1′-rac-glycerol) (ammonium salt)

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About This Item

Fórmula empírica (notación de Hill):
C43H80NO10P
Número de CAS:
1246304-50-6
Peso molecular:
802.07
UNSPSC Code:
12352211
NACRES:
NA.25

form

methanol solution

packaging

pkg of 1 × 1 mL (LM1202-1EA)

manufacturer/tradename

Avanti Research™ - A Croda Brand

concentration

~10 μg/mL (Refer to C of A for lot specific concentration.)

application(s)

lipidomics
metabolomics

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCC(O)CO)=O)(OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCCC)=O.[NH4+]

Categorías relacionadas

General description

Phosphatidylglycerol (PG) is mostly found in the pulmonary surfactant and localized to the alveoli.

Application

17:0-20:4 PG or 1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1′-rac-glycerol):
  • has been used as an internal standard (IS) in lipid extraction from isolated pure mitochondria for mass spectrometry (MS) analysis
  • has been used as an internal standard (IS) in liquid chromatography (LC)-MS analysis
  • might be used in dual substrate (acyl-CoA and lysophospholipid) choice acyltransferase assay
  • might be used for quantitative phospholipid analysis by MS

Biochem/physiol Actions

Phosphatidylglycerol (PG) is known to be involved in the inflammatory mechanism and offers protection against viral infection.

Packaging

2 mL Amber Glass Sealed Ampule (LM1202-1EA)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

also commonly purchased with this product

Referencia del producto
Descripción
Precios

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes

Storage Class

3 - Flammable liquids

wgk_germany

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Christoph Potting et al.
Cell metabolism, 18(2), 287-295 (2013-08-13)
Cardiolipin (CL), a mitochondria-specific glycerophospholipid, is required for diverse mitochondrial processes and orchestrates the function of various death-inducing proteins during apoptosis. Here, we identify a complex of the p53-regulated protein TRIAP1 (p53CSV) and PRELI in the mitochondrial intermembrane space (IMS)
Milena Vukotic et al.
Molecular cell, 67(3), 471-483 (2017-07-18)
Mutations in mitochondrial acylglycerol kinase (AGK) cause Sengers syndrome, which is characterized by cataracts, hypertrophic cardiomyopathy, and skeletal myopathy. AGK generates phosphatidic acid and lysophosphatidic acid, bioactive phospholipids involved in lipid signaling and the regulation of tumor progression. However, the

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