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Merck

900100P

Avanti

PGE1

Avanti Research - A Croda Brand 900100P, powder

Sinónimos:

Prostaglandin E1

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About This Item

Fórmula empírica (notación de Hill):
C20H34O5
Número de CAS:
Peso molecular:
354.48
UNSPSC Code:
12352211
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 1 mg (900100P-1mg)

manufacturer/tradename

Avanti Research - A Croda Brand 900100P

lipid type

neutral glycerides
neutral lipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

O=C1[C@H](CCCCCCC(O)=O)[C@@H](/C=C/[C@H](CCCCC)O)[C@H](O)C1

InChI

1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17+,19+/m0/s1

InChI key

GMVPRGQOIOIIMI-DWKJAMRDSA-N

General description

Prostaglandins (PGs) belong to the group of biological compounds called eicosanoids, which are oxygen derivatives formed during arachidonic acid metabolism. PGs are localized to every tissue and body fluids in the mammals. It was first discovered in the human prostate gland, and hence got its name, prostaglandins.

Application

Prostaglandin E1 (PGE1) might be used to study its ability to form silver adducts. It is also suitable for use in chemotaxis assays.

Biochem/physiol Actions

Prostaglandins (PGs) mediate vasodilation and vasoconstriction, the E-series of prostaglandin is a highly effective vasodilator. It is known to efficiently cause erythema. PGE1 is considered as a potent pyretic factor, and acts through cerebral ventricles. It is useful to prolong cardiovascular function in newborn suffering from ductus-dependant congenital heart disease until surgery. It acts as a vasodilator. PGE1 shows Ca2+ transients in sperm as induced by progesterone.

Packaging

5 mL Amber Glass Screw Cap Vial (900100P-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbones

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Polina V Lishko et al.
Nature, 471(7338), 387-391 (2011-03-18)
Steroid hormone progesterone released by cumulus cells surrounding the egg is a potent stimulator of human spermatozoa. It attracts spermatozoa towards the egg and helps them penetrate the egg's protective vestments. Progesterone induces Ca(2+) influx into spermatozoa and triggers multiple
David Stanley
Annual review of entomology, 51, 25-44 (2005-12-08)
Prostaglandins and other eicosanoids are oxygenated metabolites of certain polyunsaturated fatty acids. These compounds are well known for their important actions in mammalian physiology and disease. Recent work has revealed the presence and biological actions of eicosanoids in insects and
The Prostaglandins (2013)
Ayanna U Jackson et al.
Analytical and bioanalytical chemistry, 399(1), 367-376 (2010-11-12)
Spray solvent doped with silver ions increases the ease of olefin detection by desorption electrospray ionization (DESI). Characteristic silver adducts were generated in up to 50 times greater abundance when compared to conventional DESI spray solvents for the biologically significant

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