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890870C

Avanti

16:0 TAP

Avanti Polar Lipids 890870C

Sinónimos:

1,2-dipalmitoyl-3-trimethylammonium-propane (chloride salt)

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About This Item

Fórmula empírica (notación de Hill):
C38H76NO4Cl
Número de CAS:
139984-36-4
Peso molecular:
646.47
UNSPSC Code:
12352211
NACRES:
NA.25

form

liquid

packaging

pkg of 1 × 2.5 mL (890870C-25mg)

manufacturer/tradename

Avanti Polar Lipids 890870C

concentration

10 mg/mL (890870C-25mg)

lipid type

cationic lipids
transfection

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H]C(C[N+](C)(C)C)(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Cl-]

Categorías relacionadas

General description

1,2-dipalmitoyl-3-trimethylammonium-propane (16:0 TAP) is a cationic lipid and a diol based transfection reagent.

Application

1,2-dipalmitoyl-3-trimethylammonium-propane (16:0 TAP) is suitable to prepare lipid monolayer/liposome:
  • to mimic the presence of the cationic charge localized in the membrane for understanding the electrostatic effects in the biological membranes and to study its interaction with zearalenone and selenate ions
  • to study its effect on the L-pro catalyzed reaction
  • to serve as a positive control, to determine the effectiveness of anionic phospholipids for pro-inflammatory responses

Biochem/physiol Actions

1,2-dipalmitoyl-3-trimethylammonium-propane (16:0 TAP) liposomes are known to promote elevated pro-inflammatory responses.

Packaging

5 mL Clear Glass Sealed Ampule (890870C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system

Storage Class

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk_germany

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Chun Liufu et al.
International journal of nanomedicine, 14, 8923-8941 (2019-12-10)
Cancer stem cells (CSCs) are responsible for cancer therapeutic resistance and metastasis. To date, in addition to surgery, chemotherapy, and radiotherapy, gene delivery has emerged as a potential therapeutic modality for ovarian cancer. Efficient and safe targeted gene delivery is
Bao Zhu et al.
Chemosphere, 247, 125876-125876 (2020-01-25)
Aluminium oxide nanoparticles (Al2O3 NPs) potentially cause health hazards after their release into the environment. The crystalline phase of Al2O3 NPs determines their surface structure and the number of functional groups. The adsorption of natural organic matter (NOM) or biomolecules
A E Regelin et al.
Biochimica et biophysica acta, 1464(1), 151-164 (2000-03-08)
In order to investigate the relationship between lipid structure and liposome-mediated gene transfer, we have studied biophysical parameters and transfection properties of monocationic DOTAP analogs, systematically modified in their non-polar hydrocarbon chains. Stability, size and (by means of anisotropy profiles)

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