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Merck

870724P

Avanti

24:0 Coenzyme A

Avanti Research - A Croda Brand 870724P, powder

Sinónimos:

lignoceroyl Coenzyme A (ammonium salt)

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About This Item

Fórmula empírica (notación de Hill):
C45H91N10O17P3S
Número de CAS:
Peso molecular:
1169.25
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 25 mg (870724P-25mg)
pkg of 1 × 5 mg (870724P-5mg)

manufacturer/tradename

Avanti Research - A Croda Brand 870724P

application(s)

lipidomics

lipid type

coenzymes

shipped in

dry ice

storage temp.

−20°C

SMILES string

O[C@@](C(NCCC(NCCSC(CCCCCCCCCCCCCCCCCCCCCCC)=O)=O)=O)(C(C)(COP([O-])(OP([O-])(OC[C@H]([C@H]1OP([O-])(O)=O)O[C@H]([C@@H]1O)N2C3=C(C(N)=NC=N3)N=C2)=O)=O)C)[H].[NH4+].[NH4+].[NH4+]

InChI

1S/C45H82N7O17P3S.3H3N/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24-25-36(54)73-29-28-47-35(53)26-27-48-43(57)40(56)45(2,3)31-66-72(63,64)69-71(61,62)65-30-34-39(68-70(58,59)60)38(55)44(67-34)52-33-51-37-41(46)49-32-50-42(37)52;;;/h32-34,38-40,44,55-56H,4-31H2,1-3H3,(H,47,53)(H,48,57)(H,61,62)(H,63,64)(H2,46,49,50)(H2,58,59,60);3*1H3/t34-,38?,39+,40+,44-;;;/m1.../s1

InChI key

BMXJUIXYBGOZPL-SJDXFXGUSA-N

General description

24:0 Coenzyme A, also referred as lignoceroyl coenzyme A, is a long chain fatty acyl CoA and derivative of lignoceric acid. It is a metabolic intermediate of hydroxyceramide synthesis.

Application

24:0 Coenzyme A has been used as a substrate in fatty acyl-CoA reductase (AmFAR1) enzyme assay and ceramide synthase assay.

Packaging

5 mL Amber Glass Screw Cap Vial (870724P-25mg)
5 mL Amber Glass Screw Cap Vial (870724P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids


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H Shigematsu et al.
The International journal of biochemistry, 22(12), 1427-1432 (1990-01-01)
1. The enzymatic mechanism of the alpha-hydroxylation of lignoceroyl-CoA, an intermediate in the synthesis of hydroxyceramide, was studied. In the presence of NADPH, sphingosine and microsomes from 20-day-old rat brain, 14C from [1-14C]lignoceroyl-CoA was incorporated into hydroxyceramide. 2. The alpha-hydroxylation

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