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868584P

Avanti

16:0-d31 SM

Avanti Polar Lipids 868584P, powder

Sinónimos:

N-palmitoyl-d31-D-erythro-sphingosylphosphorylcholine

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About This Item

Fórmula empírica (notación de Hill):
C39H48N2O6PD31
Número de CAS:
807617-46-5
Peso molecular:
734.22
UNSPSC Code:
12352211
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 1 mg (868584P-1mg)
pkg of 1 × 5 mg (868584P-5mg)

manufacturer/tradename

Avanti Polar Lipids 868584P

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])=O)COP([O-]

Categorías relacionadas

General description

16:0-d31 SM or N-palmitoyl-d31-D-erythro-sphingosylphosphorylcholine is a deuterium labeled N-palmitoyl-sphingomyelin (SM). N-palmitoyl-SM is a sphingomyelin containing N-linked acyl chain with 16C atoms. Sphingomyelin is found in the outer leaflet of the mammalian cell membrane. It is a vital structural constituent of neurons and lipid bilayers.

Application

16:0-d31 SM or N-palmitoyl-d31-D-erythro-sphingosylphosphorylcholine has been used as an internal standard in mass spectrometry to quantify lipids in biological samples.

Packaging

5 mL Amber Glass Screw Cap Vial (868584P-1mg)
5 mL Amber Glass Screw Cap Vial (868584P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Structure and lipid interaction of N-palmitoylsphingomyelin in bilayer membranes as revealed by 2H-NMR spectroscopy
Mehnert T, et al.
Biophysical Journal, 90(3), 939-946 (2006)
J Peter Slotte
Biochimica et biophysica acta, 1858(2), 304-310 (2015-12-15)
Sphingomyelin is an important constituent of mammalian cell membranes. Its molecular structure is N-acyl-D-erythro-sphingosylphosphorylcholine. The N-acyls in sphingomyelin often contain 16-24 carbons that are mostly saturated chains; however, the monounsaturated 24:1(Δ15c) acyl chain is also common. In addition to the
Nadine Beckmann et al.
International journal of molecular sciences, 20(24) (2019-12-15)
Farber disease is a rare lysosomal storage disorder resulting from acid ceramidase deficiency and subsequent ceramide accumulation. No treatments for Farber disease are clinically available, and affected patients have a severely shortened lifespan. We have recently reported a novel acid
Kotaro Hama et al.
Journal of lipid research, 61(4), 523-536 (2020-02-23)
X-linked adrenoleukodystrophy (X-ALD) is an inherited disorder caused by deleterious mutations in the ABCD1 gene. The ABCD1 protein transports very long-chain FAs (VLCFAs) from the cytosol into the peroxisome where the VLCFAs are degraded through β-oxidation. ABCD1 dysfunction leads to

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