860571P

C24:1 Mono-Sulfo Galactosyl(β) Ceramide (d18:1/24:1)

Avanti Research^™ - A Croda Brand 860571P, powder

• Sinónimos: 3-O-sulfo-D-galactosyl-β1-1′-N-nervonoyl-D-erythro-sphingosine (ammonium salt), (synthetic)
• Fórmula empírica (notación de Hill): C₄₈H₉₄N₂O₁₁S
• Número de CAS: 1246355-69-0
• Peso molecular: 907.33
• UNSPSC Code: 12352211
• NACRES: NA.25

Propiedades

• form: powder
• packaging: pkg of 1 × 1 mg (860571P-1mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 860571P
• lipid type: sphingolipids
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: [H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCC/C=C\CCCCCCCC)=O)CO[C@H](O1)[C@H](O)[C@@H](OS([O-])(=O)=O)[C@H]([C@H]1CO)O.[NH4+]
• InChI: 1S/C48H91NO11S.H3N/c1-3-5-7-9-11-13-15-17-18-19-20-21-22-23-24-26-28-30-32-34-36-38-44(52)49-41(42(51)37-35-33-31-29-27-25-16-14-12-10-8-6-4-2)40-58-48-46(54)47(60-61(55,56)57)45(53)43(39-50)59-48;/h17-18,35,37,41-43,45-48,50-51,53-54H,3-16,19-34,36,38-40
• InChI key: MQKRPROAXITSNY-ZLGWSYPSSA-N

Descripción

General description

3-O-sulfogalactosylceramide, also known as sulfatide is a sulfoglycolipid. It was first isolated from the human brain. Sulfatide is present mainly in the cellular membrane, Golgi apparatus and lysosomes. It is produced by ceramide galactosyltransferase and cerebroside sulfotransferase.

Application

C24:1 Mono-Sulfo Galactosyl(β) Ceramide (d18:1/24:1) has been used in the stimulation of leukocyte mono-immunoglobulin (Ig)-like receptor 5 (LMIR5). It may be used as a lipid standard in matrix-assisted laser desorption ionization (MALDI) analysis of mouse brain tissues.

Biochem/physiol Actions

Sulfatide plays a vital role in the biological functions of microbial infection, hemostasis, nervous system and immune system. Accumulation of lysosomal sulfatide is associated with metachromatic leukodystrophy (MLD). Sulfatide is implicated in protein trafficking, signal transduction and neuronal cell differentiation.

Packaging

5 mL Amber Glass Screw Cap Vial (860571P-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable