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860491P

Avanti

D-ribo-Phytosphingosine-1-Phosphate

Avanti Research™ - A Croda Brand 860491P, powder

Sinónimos:

4-hydroxysphinganine-1-phosphate (Saccharomyces Cerevisiae)

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About This Item

Fórmula empírica (notación de Hill):
C18H40NO6P
Número de CAS:
383908-62-1
Peso molecular:
397.49
UNSPSC Code:
12352211
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 1 mg (860491P-1mg)
pkg of 1 × 5 mg (860491P-5mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 860491P

lipid type

sphingolipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

O[C@]([H])(CCCCCCCCCCCCCC)[C@](O)([H])[C@]([NH3+])([H])COP([O-])(O)=O

InChI

1S/C18H40NO6P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-17(20)18(21)16(19)15-25-26(22,23)24/h16-18,20-21H,2-15,19H2,1H3,(H2,22,23,24)/t16-,17+,18-/m0/s1

InChI key

AYGOSKULTISFCW-KSZLIROESA-N

General description

D-ribo-Phytosphingosine-1-Phosphate (phS1P) is a ligand for the sphingosine-1-phosphate receptor 4. It is present in the membrane of plants, fungi, mammalian tissues and bacteria.

Application

D-ribo-Phytosphingosine-1-Phosphate is suitable for use as a ligand for sphingosine-1-phosphate receptor 4 in competition binding studies. It is also suitable for use as an internal standard for the quantification of spingoid bases in maize samples using mass spectrometry and reverse phase high-performance liquid chromatography

Biochem/physiol Actions

D-ribo-Phytosphingosine-1-Phosphate (phS1P) plays a key role in cell growth. In yeast, it coordinates response to heat stress.

Packaging

5 mL Amber Glass Screw Cap Vial (860491P-1mg)
5 mL Amber Glass Screw Cap Vial (860491P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Asymmetric synthesis of d-ribo-phytosphingosine from 1-tetradecyne and (4-methoxyphenoxy) acetaldehyde
Liu Z, et al.
The Journal of Organic Chemistry, 75(13), 4356-4364 (2010)
Maize seedling blight induced by Fusarium verticillioides: Accumulation of fumonisin B1 in leaves without colonization of the leaves
Baldwin TT, et al.
Journal of Agricultural and Food Chemistry, 62(9), 2118-2125 (2014)
Translocation of sphingoid bases and their 1-phosphates, but not fumonisins, from roots to aerial tissues of maize seedlings watered with fumonisins
Zitomer NC, et al.
Journal of Agricultural and Food Chemistry, 58(12), 7476-7481 (2010)
Pharmacological characterization of human S1P4 using a novel radioligand,[4, 5-3H]-dihydrosphingosine-1-phosphate
Fossetta J, et al.
British Journal of Pharmacology, 142(5), 851-860 (2004)
Priya Gupta et al.
Plant molecular biology, 103(1-2), 173-184 (2020-02-27)
Arabidopsis LONG-CHAIN BASE KINASE 1 (LCBK1) interacts with MEDEA, a component of PCR2 complex that negatively regulates immunity. LCBK1 phosphorylates phytosphingosine and thereby promotes stomatal immunity against bacterial pathogens. Arabidopsis polycomb-group repressor complex2 (PRC2) protein MEDEA (MEA) suppresses both pattern-triggered

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