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Merck

850725C

Avanti

18:1 (Δ9-Cis) PE (DOPE)

Avanti Research - A Croda Brand

Sinónimos:

1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine; DOPE; PE(18:1(9Z)/18:1(9Z)); 110635

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About This Item

Fórmula empírica (notación de Hill):
C41H78NO8P
Número de CAS:
Peso molecular:
744.03
UNSPSC Code:
51191904
NACRES:
NA.25

description

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, chloroform solution

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (850725C-25mg)
pkg of 2 × 20 mL (850725C-1g)
pkg of 2 × 4 mL (850725C-200mg)
pkg of 5 × 4 mL (850725C-500mg)

manufacturer/tradename

Avanti Research - A Croda Brand

concentration

10 mg/mL (850725C-25mg)
25 mg/mL (850725C-1g)
25 mg/mL (850725C-200mg)
25 mg/mL (850725C-500mg)

application(s)

advanced drug delivery

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

InChI

1S/C41H78NO8P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(43)47-37-39(38-49-51(45,46)48-36-35-42)50-41(44)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h17-20,39H,3-16,21-38,42H2,1-2H3,(H,45,46)/b19-17-,20-18-/t39-/m1/s1

InChI key

MWRBNPKJOOWZPW-NYVOMTAGSA-N

Application

18:1 (Δ9-Cis) PE (DOPE) has been used:
  • as a lipid standard in the optimization of the liquid chromatography–mass spectrometry (LC-MS)
  • to investigate its impact on antiphosphatidylethanolmine (aPE) enzyme-linked immunosorbent assay (ELISA)
  • to measure its monolayer spontaneous curvature C0s

Packaging

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (850725C-1g)
5 mL Clear Glass Sealed Ampule (850725C-200mg)
5 mL Clear Glass Sealed Ampule (850725C-25mg)
5 mL Clear Glass Sealed Ampule (850725C-500mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

also commonly purchased with this product

Referencia del producto
Descripción
Precios

pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Visite la Librería de documentos

Differential dependencies on [Ca 2+] and temperature of the monolayer spontaneous curvatures of DOPE, DOPA and cardiolipin: effects of modulating the strength of the inter-headgroup repulsion
Chen YF, et al.
Soft Matter, 11(20), 4041-4053 (2015)
Jamie Burrell et al.
Langmuir : the ACS journal of surfaces and colloids, 33(44), 12804-12813 (2017-10-06)
Oxylipins, or fatty aldehydes, are a class of molecules produced from membrane lipids as a result of oxidative stress or enzyme-mediated peroxidation. Here we report the effects of two biologically important fatty aldehydes, trans,trans-2,4-decanedienal (DD) and cis-11-hexadecenal (HD), on the
Matthias Dittrich et al.
Langmuir : the ACS journal of surfaces and colloids (2018-09-01)
Colloidal nucleic acid carrier systems based on cationic lipids are a promising pharmaceutical tool in the implementation of gene therapeutic strategies. This study demonstrates the complex behavior of DNA at the lipid-solvent interface facilitating structural changes of the lyotropic liquid-crystalline
Tatiana K Rostovtseva et al.
The Journal of biological chemistry, 287(35), 29589-29598 (2012-07-06)
Elucidating molecular mechanisms by which lipids regulate protein function within biological membranes is critical for understanding the many cellular processes. Recently, we have found that dimeric αβ-tubulin, a subunit of microtubules, regulates mitochondrial respiration by blocking the voltage-dependent anion channel
The outcome of ELISA for antiphosphatidylethanolamine antibodies is dependent on the composition of phosphatidylethanolamine
Hou S, et al.
Journal of Immunological Methods, 440, 27-34 (2017)

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