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840044P

Avanti

Soy PI

Avanti Research™ - A Croda Brand

Sinónimos:

L-α-phosphatidylinositol (Soy) (sodium salt)

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About This Item

Número de CAS:
383907-36-6
UNSPSC Code:
12352211
NACRES:
NA.25

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 10 mg (840044P-10mg)
pkg of 2 × 100 mg (840044P-200mg)
pkg of 1 × 25 mg (840044P-25mg)
pkg of 1 × 50 mg (840044P-50mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand

lipid type

phosphoglycerides

shipped in

dry ice

storage temp.

−20°C

SMILES string

O[C@H]1[C@@H]([C@H](O)[C@H](O)[C@@H](O)[C@@H]1O)OP([O-])(OC[C@@]([H])(COC(CCCCCCCCCCCCCCC)=O)OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)=O.[Na+]

InChI

1S/C43H79O13P.Na/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-37(45)55-35(34-54-57(51,52)56-43-41(49)39(47)38(46)40(48)42(43)50)33-53-36(44)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2;/h11,13,17-18,35,38-43,46-50H,3-10,12,14-16,19-34H2,1-2H3,(H,51,52);/q;+1/p-1/b13-11-,18-17-;/t35-,38?,39-,40?,41?,42?,43-;/m1./s1

InChI key

DCDQYHYLAGWAPO-UQZYTPKFSA-M

Categorías relacionadas

General description

L-α-phosphatidylinositol (Soy) is a negatively charged, naturally occurring glycerophospholipid with an inositol ring. It is found in biological membranes, which takes part in scaffolding, cellular compartmentalization, and signal transduction.

Application

Soy PI has been used in the preparation of liposomes.

Biochem/physiol Actions

L-α-phosphatidylinositol (Soy) plays a key role as a cellular mediator during signal transduction processes. It is used to design therapeutic delivery vehicle for drug delivery. Soy PI also contributes to the regulation of cholesterol metabolism.

Packaging

5 mL Clear Glass Sealed Ampule (840044P-10mg)
5 mL Clear Glass Sealed Ampule (840044P-200mg)
5 mL Clear Glass Sealed Ampule (840044P-25mg)
5 mL Clear Glass Sealed Ampule (840044P-50mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Cell-free synthesis and functional characterization of sphingolipid synthases from parasitic trypanosomatid protozoa.
Sevova ES, et al.
The Journal of Biological Chemistry, 285(27), 20580-20587 (2010)
Aaron Peng et al.
Chemistry and physics of lipids, 165(1), 15-22 (2011-10-26)
Liposomes consisted of phosphatidylinositol (PI) and phosphatidylcholine (PC) have been utilized as delivery vehicle for drugs and proteins. In the present work, we studied the effect of soy PI on physical properties of 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) liposomes such as phase state
Reorganization of Ternary Lipid Mixtures of Nonphosphorylated Phosphatidylinositol Interacting with Angiomotin
Kimble-Hill, et al.
The Journal of Physical Chemistry B, 122(35), 8404-8415 (2018)
Ashutosh Tripathi et al.
The Journal of biological chemistry, 294(50), 19081-19098 (2019-11-07)
Phosphatidylinositol-transfer proteins (PITPs) are key regulators of lipid signaling in eukaryotic cells. These proteins both potentiate the activities of phosphatidylinositol (PtdIns) 4-OH kinases and help channel production of specific pools of phosphatidylinositol 4-phosphate (PtdIns(4)P) dedicated to specific biological outcomes. In
Phospholipids as cardiovascular therapeutics
Pandey NR and Sparks DL
Current Opinion in Investigational Drugs, 9(3), 281-285 (2008)
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