810251P

NBD-6 Cholesterol

Avanti Polar Lipids 810251P, powder

• Sinónimos: 5-cholesten-3β-ol 6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]caproate
• Fórmula empírica (notación de Hill): C₃₉H₅₈N₄O₅
• Número de CAS: 201731-19-3
• Peso molecular: 662.90
• UNSPSC Code: 12352211
• NACRES: NA.25

Propiedades

• assay: >99% (TLC)
• form: powder
• packaging: pkg of 1 × 1 mg (810251P-1mg)
• manufacturer/tradename: Avanti Polar Lipids 810251P
• shipped in: dry ice
• storage temp.: −20°C

Descripción

General description

NBD-6 Cholesterol is a fluorescent analog of the lipoprotein compound cholesterol, with NBD (2-(4-nitro-2,1,3-benzoxadiazol-7-yl) aminoethyl) being the fluorescent group.

Application

NBD-6 Cholesterol has been used for NBD-cholesterol binding assay, to study the binding of fluorescent NBD cholesterol in the binding pocket concerning ASTER domains.

Biochem/physiol Actions

Cholesterol is produced from acetyl-CoA by a complex multistep mevalonate pathway. In mammals, liver is the main site of de novo cholesterol synthesis contributing to almost 80% of total cholesterol synthesis. Cholesterol and its metabolites, along with its precursors, play important roles in cellular membrane physiology. They also have roles in reproductive biology, dietary nutrient absorption, stress responses, salt and water balance and calcium metabolism.

Packaging

5 mL Amber Glass Screw Cap Vial (810251P-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Información de seguridad

• Storage Class: 11 - Combustible Solids