810219P
Avanti
C12-NBD Sphingomyelin
Avanti Research™ - A Croda Brand 810219P, powder
Sinónimos:
N-[12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl]-sphingosine-1-phosphocholine
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About This Item
Fórmula empírica (notación de Hill):
C41H73N6O9P
Número de CAS:
Peso molecular:
825.03
UNSPSC Code:
12352211
NACRES:
NA.25
Productos recomendados
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (810219P-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 810219P
shipped in
dry ice
storage temp.
−20°C
Categorías relacionadas
General description
C12-NBD Sphingomyelin is a fluorescent analog of biologically active molecule, sphingomyelin. Sphingomyelin is predominantly found in the animal plasma membrane. It is abundantly present as component of cell membranes in mammals, nematodes, protozoa.
Application
C12-NBD-sphingomyelin has been used as a substrate to test substrate specificity of neutral ceramidase orthologue encoded by AsahA gene.
Biochem/physiol Actions
Sphingomyelin (SM) is produced from phosphatidylcholine and ceramide on the cell surface and in lumen of the Golgi. SM′s high packing density and affinity to sterols form a rigid barrier to the extracellular environment. SM is also involved in the formation of lipid rafts in cell membranes, which perform important functions in signal transduction and membrane trafficking.
Packaging
5 mL Amber Glass Screw Cap Vial (810219P-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class
11 - Combustible Solids
Certificados de análisis (COA)
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FEMS microbiology letters, 298(2), 157-165 (2009-08-05)
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