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810155C

Avanti

18:1-06:0 NBD PE

Avanti Research™ - A Croda Brand 810155C

Sinónimos:

1-oleoyl-2-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-phosphoethanolamine

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About This Item

Fórmula empírica (notación de Hill):
C35H58N5O11P
Número de CAS:
106918-68-7
Peso molecular:
755.84
UNSPSC Code:
12352211
NACRES:
NA.25

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (810155C-1mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 810155C

concentration

1 mg/mL (810155C-1mg)

shipped in

dry ice

storage temp.

−20°C

Categorías relacionadas

General description

N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) phosphoethanolamine (NBD PE) is a fluorescent probe where the fluorescent NBD label is attached to the headgroup of phosphatidylethanolamine. The NBD moiety is known to localize to the membrane interface. Phosphoethanolamine is the second most abundant andmetabolically related aminophospholipid. It is mostly enriched in brain.

Application

18:1-06:0 NBD PE has been used as a liposomal supplement for protein reconstitution into liposomes and scrambling experiments. It may also be used to analyse the temporal fluorescent pattern of Chol-E-NBD.

Biochem/physiol Actions

N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) phosphoethanolamine (NBD PE) plays a vital role as a fluorescent probe in the studies of organization and dynamics of membranes. Phosphoethanolamine (PE) acts as a substrate for several phospholipids of the cell membrane.

Packaging

5 mL Amber Glass Screw Cap Vial (810155C-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

wgk_germany

WGK 3

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Certificados de análisis (COA)

Lot/Batch Number

Lo sentimos, en este momento no disponemos de COAs para este producto en línea.

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Formation and function of phosphatidylserine and phosphatidylethanolamine in mammalian cells
Vance JE and Tasseva G
The FEBS journal, 37-50 (2012)
Fluorescent methods to study biological membranes, 37-50 (2012)
Synthetic phosphoethanolamine induces cell cycle arrest and apoptosis in human breast cancer MCF-7 cells through the mitochondrial pathway
Ferreira AK, et al.
Biomedicine and Pharmacotherapy, 37-50 (2012)
Bieong-Kil Kim et al.
Bioorganic & medicinal chemistry letters, 25(18), 3893-3896 (2015-08-06)
Cholesterol-based fluorescent lipids with ether linker were synthesized using NBD (Chol-E-NBD) or Rhodamine B (Chol-E-Rh), and the usefulnesses as fluorescent probes for tracing cholesterol-based liposomes were validated. The fluorescent intensities of liposomes containing these modified lipids were measured and observed
Cardiolipin and phosphatidylethanolamine role in dibucaine interaction with the mitochondrial membrane
Lopes SC, et al.
Biochimica et biophysica acta. General subjects, 37-50 (2012)
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