141101C

Brain Extract Polar

Avanti Research^™ - A Croda Brand

• Sinónimos: Brain Polar Lipid Extract (Porcine)
• Número de CAS: 86088-88-2
• UNSPSC Code: 12352211
• NACRES: NA.25

Propiedades

• form: chloroform solution
• packaging: pkg of 1 × 4 mL (141101C-100mg); pkg of 5 × 4 mL (141101C-500mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand
• concentration: 25 mg/mL (141101C-100mg); 25 mg/mL (141101C-500mg)
• lipid type: lipid extracts
• shipped in: dry ice
• storage temp.: −20°C

Descripción

General description

Brain Extract Polar comprises phosphatidylethanolamine as major lipid component. It also contains phosphatidylserine and phosphatidylcholine. The minor components include the phosphatidic acid and phosphatidylinositol.

Brain Polar Lipid Extract is derived from the total lipid extract by precipitation with acetone followed by extraction of the acetone insoluble material with diethyl ether.

Application

Brain Extract Polar has been used as an artificial membrane solution component for permeability studies. It may be used for coating donor plate during parallel artificial membrane permeability assay (PAMPA) to study blood-brain barrier penetration. It may be used in liposome preparation for dynamin self-assembly assay.

Biochem/physiol Actions

Brain lipid, especially the polar fraction plays a key role in the inhibition of prion seeded amyloid formation. Lipid extracts from the mammalian tissues like brain, kidney and liver are used in generating model membranes for mimicking real membranes.

Packaging

5 mL Clear Glass Sealed Ampule (141101C-100mg)

5 mL Clear Glass Sealed Ampule (141101C-500mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Información de seguridad

• pictograms: GHS06,GHS08
• signalword: Danger
• hcodes: H302,H315,H319,H331,H336,H351,H361d,H372,H412
• pcodes: P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• target_organs: Central nervous system, Liver,Kidney
• Storage Class: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• wgk_germany: WGK 3
• flash_point_f: does not flash
• flash_point_c: does not flash