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Merck

S5502

Sigma-Aldrich

Succinic dihydrazide

96%

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About This Item

Fórmula lineal:
H2NNHCOCH2CH2CONHNH2
Número de CAS:
Peso molecular:
146.15
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

assay

96%

mp

170-171 °C (lit.)

SMILES string

NNC(=O)CCC(=O)NN

InChI

1S/C4H10N4O2/c5-7-3(9)1-2-4(10)8-6/h1-2,5-6H2,(H,7,9)(H,8,10)

InChI key

HCOMFAYPHBFMKU-UHFFFAOYSA-N

Categorías relacionadas

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Elena A Khomyakova et al.
Nucleosides, nucleotides & nucleic acids, 30(7-8), 577-584 (2011-09-06)
An efficient method for the synthesis of DNA or RNA oligonucleotide 2'-hydrazides is described. Fully deprotected oligonucleotides containing a hydrazide group at the 2'-position of a uridine residue were obtained by a novel two-step procedure: periodate cleavage of an oligonucleotide
M F Turchinskiĭ et al.
Bioorganicheskaia khimiia, 15(10), 1341-1345 (1989-10-01)
A two-step chemical method of introduction of nonradioactive labels in DNA was proposed. At first step DNA is modified by succinic dihydrazide at pH 5.0 and 95 degrees C, or at pH 4.5 and 37 degrees C in presence of
Marlene Lopes et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 113, 88-96 (2016-12-23)
This study aimed to assess the biodistribution of antihyperglycemic insulin-loaded alginate/dextran sulfate-based nanoparticles dual coated with chitosan and technetium-99m-albumin (
N Yoshitani et al.
Analytical biochemistry, 277(1), 127-134 (1999-12-28)
We developed a convenient method for the synthesis of dextran-based multivalent probes containing N-linked oligosaccharides which is efficient even in a small scale. Oligosaccharides were derivatized with succinic dihydrazide and dimethylamine borane under a mild acidic condition. The derivatized oligosaccharides
Leeanne McGurk et al.
Molecular cell, 71(5), 703-717 (2018-08-14)
In amyotrophic lateral sclerosis (ALS) and frontotemporal degeneration (FTD), cytoplasmic aggregates of hyperphosphorylated TDP-43 accumulate and colocalize with some stress granule components, but how pathological TDP-43 aggregation is nucleated remains unknown. In Drosophila, we establish that downregulation of tankyrase, a poly(ADP-ribose)

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