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Merck

K6000

Sigma-Aldrich

α-Keto-γ-(methylthio)butyric acid sodium salt

≥97%

Sinónimos:

4-Methylthio-2-oxobutanoic acid sodium salt, 4-Methylthio-2-oxobutyric acid sodium salt, KMBA

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About This Item

Fórmula lineal:
C5H7O3SNa
Número de CAS:
Peso molecular:
170.16
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

assay

≥97%

storage temp.

2-8°C

SMILES string

[Na].CSCCC(=O)C(O)=O

InChI

1S/C5H8O3S.Na/c1-9-3-2-4(6)5(7)8;/h2-3H2,1H3,(H,7,8);/q;+1/p-1

InChI key

IFSCKRWNXKWTLR-UHFFFAOYSA-M

General description

α-Keto-γ-methylthiobutyric acid (KMTB) is a keto derivative of L-methionine that shows considerable potential as a substitute for L-methionine. The sodium salt of KMTB can be employed in nucleophilic substitution reactions. Additionally, it acts as a building block for the synthesis of amino acids, peptides, and other complex organic compounds.

Application


  • Measuring antioxidant capacity using the ORAC and TOSC assays.: This study details the use of α-Keto-γ-(methylthio)butyric acid sodium salt in assessing antioxidant capacity through ORAC and TOSC assays, emphasizing its utility in metabolic and chemical synthesis research (Garrett AR et al., 2010).

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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The Journal of nutrition, 137(8), 1868-1873 (2007-07-20)
Relative bioefficacy and toxicity of Met precursor compounds were investigated in young chicks. The effectiveness of DL-Met and 2-keto-4-(methylthio)butyric acid (Keto-Met) to serve as L-Met precursors was quantified using Met-deficient diets of differing composition. Efficacy was based on slope-ratio and
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Proceedings of the National Academy of Sciences of the United States of America, 102(45), 16158-16163 (2005-11-02)
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