G10105

18β-Glycyrrhetinic acid

97%

• Sinónimos: 3β-Hydroxy-11-oxo-18β,20β-olean-12-en-29-oic acid, Enoxolone, Glycyrrhetin, Subglycyrrhelinic acid, Uralenic acid
• Fórmula empírica (notación de Hill): C₃₀H₄₆O₄
• Número de CAS: 471-53-4
• Peso molecular: 470.68
• Beilstein/REAXYS Number: 2229654
• EC Number: 207-444-6
• MDL number: MFCD00003706
• UNSPSC Code: 12352115
• PubChem Substance ID: 24895033
• NACRES: NA.22

Propiedades

• assay: 97%
• optical activity: [α]22/D +170.0°, c = 1 in chloroform
• mp: 292-295 °C (lit.)
• SMILES string: CC1(C)[C@@H](O)CC[C@@]2(C)[C@H]1CC[C@]3(C)[C@@H]2C(=O)C=C4[C@@H]5C[C@](C)(CC[C@]5(C)CC[C@@]34C)C(O)=O
• InChI: 1S/C30H46O4/c1-25(2)21-8-11-30(7)23(28(21,5)10-9-22(25)32)20(31)16-18-19-17-27(4,24(33)34)13-12-26(19,3)14-15-29(18,30)6/h16,19,21-23,32H,8-15,17H2,1-7H3,(H,33,34)/t19-,21-,22-,23+,26+,27-,28-,29+,30+/m0/s1
• InChI key: MPDGHEJMBKOTSU-YKLVYJNSSA-N
• Gene Information: human ... HSD11B1(3290) , HSD11B2(3291) ; rat ... Hsd11b1(25116) , Hsd11b2(25117)

Descripción

General description

18β-Glycyrrhetinic acid is a pentacyclic triterpenoid found in the Glycyrrhiza glabra L.(liquorice) roots. It is the key metabolite of glycyrrhizin and glycyrrhizic acid.

Application

The product may be used as a starting material to prepare 18β-glycyrrhetinic acid derivatives, which show anti-inflammatory and antioxidant properties.

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves