937754

Poly(D,L-lactic-co-glycolic acid)-block-poly(glutamic acid)

PLGA average M_n 25,000, mol wt (PGlu average M_n 5,000), lactide:glycolide 50:50

• Sinónimos: Amphiphilic, Block polymer, Drug delivery, Glutamic acid, PLGA, PLGA-b-PGlu, Poly(glutamic acid), Polyaminoacids
• Fórmula lineal: [(C₃H₄O₂)a(C₂H₂O₂)b]n O[C₅H₇NO₃]m
• UNSPSC Code: 12162002
• NACRES: NA.21

Propiedades

• feed ratio: lactide:glycolide 50:50
• Quality Level: 100
• mol wt: PLGA average M_n 25,000; (PGlu average M_n 5,000)
• color: white to beige, powder
• storage temp.: −20°C

Descripción

Application

This polymer is a amphiphilic diblock copolymer composed of a hydrophobic PLGA block and a hydrophilic poly(glutamic acid) block. PLGA is a biocompatible and biodegradable polymer that has been approved by the FDA and the EMA for biomedical and pharmaceutical applications. Poly(glutamic acid) is biodegradable, non-toxic and non-immunogenic macromolecules. This biodegradable, biocompatible polymers can self-assemble to form nanoparticles, such as micelles and polymersomes, for drug delivery applications

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable