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Merck
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Documentos clave

926175

Sigma-Aldrich

Glycol Chitosan Methacrylate

Degree of methacrylation ∼45%

Sinónimos:

Chitosan hydrogel, Crosslinkble chitosan, Glycol chitosan, Methacrylated glycol chitosan

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About This Item

Fórmula lineal:
[C14H25NO8]n [C10H17NO6]m
UNSPSC Code:
12352201
NACRES:
NA.23

Quality Level

100

form

powder

color

white to light yellow, light brown

suitability

conforms to structure for NMR

storage temp.

2-8°C

Application

Glycol chitosan is soluble at neutral pH and possesses potentially useful biological properties such as good biocompatibility accelerate wound healing, and antimicrobial properties, and it is less toxic and provide to stimulates chondrocyte growth at low concentrations. Methacrylated glycol chitosan is photo- and thermally cross-linkable and is used as a precursor for the preparation of hydrogels used in biomedical applications including drug delivery, tissue engineering, and 3D bioprinting.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Zhilong Shi et al.
Biomaterials, 27(11), 2440-2449 (2005-12-13)
Although total joint replacement has become commonplace in recent years, bacterial infection remains a significant complication following this procedure. One approach to reduce the incidence of joint replacement infection is to add antimicrobial agents to the bone cement used to
Modified chitosan hydrogels as drug delivery and tissue engineering systems: present status and applications
Tapan Kumar Giri Amrit Thakur, et al.
Acta Pharmaceutica Sinica. B, Volume 2, Issue 5, 439-449 (2012)
K Y Lee et al.
Biomaterials, 16(16), 1211-1216 (1995-11-01)
Chitosan was selectively N-acylated with various carboxylic anhydrides, e.g., acetic, propionic, n-butyric, n-valeric and n-hexanoic anhydrides, in the presence of methanol. The degree of N-acylation of about 20-50% was obtainable without occurrence of gelation by using carboxylic anhydrides of 0.3-1.2
Brian G Amsden et al.
Biomacromolecules, 8(12), 3758-3766 (2007-11-23)
Glycol chitosan is a derivative of chitosan that is soluble at neutral pH and possesses potentially useful biological properties. With the goal of obtaining biocompatible hydrogels for use as tissue engineering scaffolds or drug delivery depots, glycol chitosan was converted
Evaluation of the Properties of Soluble Chitosan and Chitosan Microspheres
Carreno-Gomez, B.; Duncan, R
International Journal of Pharmaceutics, 148 (2), 231-240 (1997)
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