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923745

Sigma-Aldrich

INVIVO-GEL BMP2 bioink

suitable for 3D bioprinting applications

Sinónimos:

3D bioprinting, 3DBP, ECM

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About This Item

UNSPSC Code:
12352201
NACRES:
NA.23

Quality Level

storage temp.

2-8°C

Application

INVIVO-GEL BMP2 bioink is specifically developed and optimized for 3D bioprinting applications. The INVIVO-GEL BMP2 bioink kit includes optimally formulated BMP-2 mimetic peptide conjugated gelatin-based hydrogel complex packed in syringe for easy dispensing. The kit also includes Gel-linker, which reinforces mechanical stability. A transparent hydrogel forms when contents are properly mixed and exposed to UV light. This bioink is capable of generating mechanically stable 3D structures that can be maintained for days in the culture environment. BMP-2 is a potent osteoinductive growth that belongs to the transforming growth factor-â (TGF-â) protein superfamily. BMP-2 stimulates MSCs towards osteogenic differentiation, and significantly increased bone formation.

Components

INVIVO-GEL BMP2 in syringe 5mL x 2

Gel-linker(A) powder 500µL x 1

Gel-linker(B) powder 1µL x 1

pictograms

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Warning

hcodes

Hazard Classifications

Eye Irrit. 2 - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3


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Gelatin methacryloyl and its hydrogels with an exceptional degree of controllability and batch-to-batch consistency
Zhu et al.
Scientific Reports, 9 (2019)
Michelle T Poldervaart et al.
PloS one, 8(8), e72610-e72610 (2013-08-27)
The design of bioactive three-dimensional (3D) scaffolds is a major focus in bone tissue engineering. Incorporation of growth factors into bioprinted scaffolds offers many new possibilities regarding both biological and architectural properties of the scaffolds. This study investigates whether the
Shining Xiao et al.
Stem cell reviews and reports, 15(5), 664-679 (2019-06-04)
Gelatin methacrylate (GelMA)-based hydrogels are gaining a great deal of attention as potentially implantable materials in tissue engineering applications because of their biofunctionality and mechanical tenability. Since different natural tissues respond differently to mechanical stresses, an ideal implanted material would
Kan Yue et al.
Biomaterials, 73, 254-271 (2015-09-29)
Gelatin methacryloyl (GelMA) hydrogels have been widely used for various biomedical applications due to their suitable biological properties and tunable physical characteristics. GelMA hydrogels closely resemble some essential properties of native extracellular matrix (ECM) due to the presence of cell-attaching
Mengxiang Zhu et al.
Scientific reports, 9(1), 6863-6863 (2019-05-06)
Gelatin methacryloyl (GelMA) is a versatile material for a wide range of bioapplications. There is an intense interest in developing effective chemical strategies to prepare GelMA with a high degree of batch-to-batch consistency and controllability in terms of methacryloyl functionalization

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