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Merck
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Key Documents

921629

Sigma-Aldrich

Reaction chamber chip - various volume chambers

Fluidic 620, COC

Sinónimos:

Microfluidic chip

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About This Item

UNSPSC Code:
42142600
NACRES:
NA.23

description

Microfludic chip x1

Application

Chamber chips come in the format of a microscopy slide (75.5 mm x 25.5 mm x 1.5 mm) and are equipped with Mini Luer interfaces. Their key microfluidic elements are reaction chambers of various volumes. Chamber chips are the perfect tool to facilitate reactions, such as amplification of a targeted DNA during qPCR, or to extract target molecules out of a given sample in preparative quantities. These chips can, for example, be used as nucleic acid extraction devices via magnetic beads simply via applying beads and sample and by using an external magnet to hold the beads in place. These procedures can be done completely manually with a pipette – besides the magnet no additional equipment is necessary – or semi-automated with normal peristaltic pumps found in most life science labs.

Reaction chamber chip - various volume chambers, Fluidic 620, COC is made of COC (Cyclic olefin copolymer). This straight channel chip features a variety of channels within one chip with the same channel dimensions besides the channel depth. The varying channel depth and the resulting different channel volumes allow for direct comparison of the channel depth influence on the assay and the measurement. The chip is the perfect tool to help choosing the right channel dimensions in the design process of integrated microfluidic devices.

Chip Properties:
  • Mini Luer Interface
  • 16 various volume chambers
  • Material: Cyclic olefin copolymer (COC)
  • Chamber Dimensions: 2mm(width) x various depths (100-800μm) x 18mm (length)
  • Chamber Volumes: 3.6μl, 5.4μl, 7.1μl, 10.6μl, 14.1μl, 17.6μl, 21μl, 27.7μl
.

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Microfluidic-assisted fabrication of carriers for controlled drug delivery.
Santos H A, et al.
Lab on a chip, 17, 1856-1883 (2017)
Recent advances of controlled drug delivery using microfluidic platforms.
Li X, et al.
Advanced Drug Delivery Reviews, 128, 3-28 (2018)
Microfluidic-assisted fabrication of carriers for controlled drug delivery.
Santos H A, et al.
Lab on a chip, 17, 1856-1883 (2017)
Sharma T Sanjay et al.
Advanced drug delivery reviews, 128, 3-28 (2017-09-19)
Conventional systematically-administered drugs distribute evenly throughout the body, get degraded and excreted rapidly while crossing many biological barriers, leaving minimum amounts of the drugs at pathological sites. Controlled drug delivery aims to deliver drugs to the target sites at desired
Dongfei Liu et al.
Lab on a chip, 17(11), 1856-1883 (2017-05-10)
The microfluidic technique has brought unique opportunities toward the full control over the production processes for drug delivery carriers, owing to the miniaturisation of the fluidic environment. In comparison to the conventional batch methods, the microfluidic setup provides a range

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