722456

4-Bromotetrahydropyran

• Sinónimos: 4-Bromooxacyclohexane, 4-Bromotetrahydro-2H-pyran
• Fórmula empírica (notación de Hill): C₅H₉BrO
• Número de CAS: 25637-16-5
• Peso molecular: 165.03
• MDL number: MFCD07371501
• UNSPSC Code: 12352100
• PubChem Substance ID: 329763928
• NACRES: NA.22

Propiedades

• form: liquid
• Quality Level: 100
• refractive index: n20/D 1.497
• density: 1.467 g/cm³ at 25 °C
• functional group: bromo; ether
• SMILES string: BrC1CCOCC1
• InChI: 1S/C5H9BrO/c6-5-1-3-7-4-2-5/h5H,1-4H2
• InChI key: IVBVKTPDEWDNRW-UHFFFAOYSA-N

Descripción

Application

Reactant for:

• Nickel-catalyzed alkyl-alkyl Suzuki coupling reactions with boron reagents
• Preparation of a selective small-molecule melanocortin-4 receptor agonist with efficacy in a pilot study of sexual dysfunction in humans
• Preparation of aliphatic hydrocarbons via nickel-catalyzed Suzuki cross-coupling with alkylboranes
• Preparation of anthranilic acids as antibacterial agents with human serum albumin binding affinity
• Preparation of antiatherogenic antioxidant di-tert-butyldihydrobenzofuranols via Grignard reactions with di-tert-butyl(hydroxy)benzaldehyde derivatives
• Synthesis of gephyrotoxin via the Schmidt reaction

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 2
• flash_point_f: 160.0 °F - closed cup
• flash_point_c: 71.1 °C - closed cup