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181285

Sigma-Aldrich

Ácido poli(acrílico)

average Mv ~450,000

Sinónimos:

PAA

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About This Item

Fórmula lineal:
(C3H4O2)n
Número de CAS:
9003-01-4
MDL number:
MFCD00084394
UNSPSC Code:
12162002
PubChem Substance ID:
24850924
NACRES:
NA.23

crosslinking

~0.1 % cross-linked

Quality Level

200

mol wt

average Mv ~450,000

viscosity

350-2500 cP

transition temp

Tg 106 °C

InChI

1S/C3H4O2.Na/c1-2-3(4)5;/h2H,1H2,(H,4,5);/q;+1/p-1

InChI key

NNMHYFLPFNGQFZ-UHFFFAOYSA-M

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General description

Poly (acrylic acid) (PAA) is hygroscopic, brittle and colorless in nature with Tg at nearly 106oC. At temperatures above 200 to 250oC, it loses water and becomes an insoluble crosslinked polymer anhydride. Solubility of dried PAA in water increases with rise in temperatures. Concentrated solutions of PAA in water is thixotropic in nature.

Application

Poly (acrylic acid) (PAA)/Poly methyl methacrylate copolymers are used for drug delivery.
Other applications may include:
  • to study solute diffusion in Polyvinyl alcohol/PAA copolymer hydrogel
  • synthesizing poly(N-isopropylacrylamide)-block-PAA copolymer which responds to both temperature and pH stimuli
  • in preparing block copolymer of oligo (methyl methacrylate)/PAA for micellar delivery of hydrophobic drugs
  • as thickening agent for adhesives.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number
MKCQ8554
MKCQ4090
MKCP9426
MKCQ0178
MKCP5894

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Synthesis and characterization of P (MMA-AA) copolymers for targeted oral drug delivery.
Barba AA, et al.
Polymer Bull., 62(5), 679-688 (2009)
Solute diffusion in poly (vinyl alcohol)/poly (acrylic acid) interpenetrating networks.
Peppas NA, et al.
Macromolecules, 29(27), 8798-8804 (1996)
Christina M Kelliher et al.
Fungal biology, 124(5), 398-406 (2020-05-12)
Work on the filamentous fungus Neurospora crassa has contributed to or pioneered many aspects of research on circadian clock mechanism, a process that is functionally conserved across eukaryotes. Biochemical assays of the fungal circadian clock typically involve growth in liquid
T Inoue et al.
Journal of controlled release : official journal of the Controlled Release Society, 51(2-3), 221-229 (1998-08-01)
An AB block copolymer of oligo(methyl methacrylate) (oMMA) and poly(acrylic acid) (PAAc) has been synthesized. The block copolymer forms micelles in an aqueous medium, as confirmed by a fluorescence probe technique using pyrene. Doxorubicin hydrochloride was incorporated into the micelle
A New Double-Responsive Block Copolymer Synthesized via RAFT Polymerization: Poly (N-isopropylacrylamide)-b lock-poly (acrylic acid)
Schili CM, et al.
Macromolecules, 37(21), 7861-7866 (2004)
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