149837

2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline

≥99%, for peptide synthesis

• Sinónimos: N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline, EEDQ, Ethyl 1,2-dihydro-2-ethoxyquinoline-1-carboxylate
• Fórmula empírica (notación de Hill): C₁₄H₁₇NO₃
• Número de CAS: 16357-59-8
• Peso molecular: 247.29
• Beilstein/REAXYS Number: 533048
• EC Number: 240-418-2
• MDL number: MFCD00006703
• UNSPSC Code: 12352005
• PubChem Substance ID: 24848976
• NACRES: NA.22

Propiedades

• Nombre del producto: 2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline, ≥99%
• assay: ≥99%
• form: solid
• reaction suitability: reaction type: Coupling Reactions
• mp: 62-67 °C (lit.)
• application(s): peptide synthesis
• functional group: ether
• storage temp.: 2-8°C
• SMILES string: CCOC1C=Cc2ccccc2N1C(=O)OCC
• InChI: 1S/C14H17NO3/c1-3-17-13-10-9-11-7-5-6-8-12(11)15(13)14(16)18-4-2/h5-10,13H,3-4H2,1-2H3
• InChI key: GKQLYSROISKDLL-UHFFFAOYSA-N

Descripción

General description

2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline(EEDQ) is a stable, and readily available reagent used to prepare amides and peptides in high yields. At ambient temperature, EEDQ is soluble in an aqueous medium containing organic solvents but insoluble in water. It is used as a coupling agent in peptide synthesis.

Application

2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline is used as a coupling agent:

• In the regioselective quaternization of chitosan and its amphiphilic derivatives.
• In the preparation of amide-type S-MA derivative-modified QCM sensors.

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves