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TLR2

toll-like receptor 2

Sinónimos:
CD282, TIL4
Especie:
ID UniProtKB:
ID del gen:
  • Human(7097) Summary: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB. [provided by RefSeq, Jul 2008]
  • Mouse(24088) toll-like receptor 2
  • Rat(310553) toll-like receptor 2
  • Zebrafish(403125) toll-like receptor 2
  • Horse(100009701) toll-like receptor 2
  • domestic cat(493797) toll-like receptor 2
  • dog(448807) toll-like receptor 2
  • domestic guinea pig(100717682) toll-like receptor 2
  • naked mole-rat(101724657) toll-like receptor 2
  • Domestic Rabbit(100009578) toll-like receptor 2
  • cow(281534) toll-like receptor 2
  • sheep(554262) toll-like receptor 2
  • Goat(100860747) toll-like receptor 2

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-TLR2 Antibody, clone 1J19 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human
Aplicación
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-TLR2 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human TLR2,
Especie
human
MISSION® esiRNA, targeting mouse Tlr2,
Especie
mouse