BCL10
B-cell CLL/lymphoma 10
CARMEN, CIPER, CLAP, c-E10, mE10
Human BCL10 (8915), Mouse Bcl10 (12042), Rat Bcl10 (83477), chicken BCL10 (424528), cow BCL10 (540824), domestic cat BCL10 (101099570), dog BCL10 (490183), sheep BCL10 (101113372), naked mole-rat Bcl10 (101712563), domestic guinea pig Bcl10 (100729772)
- Human(8915) Summary: This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. [provided by RefSeq, Jul 2008]
- Mouse(12042) B cell leukemia/lymphoma 10
- Rat(83477) B-cell CLL/lymphoma 10
- chicken(424528) B-cell CLL/lymphoma 10
- cow(540824) B-cell CLL/lymphoma 10
- domestic cat(101099570) B-cell CLL/lymphoma 10
- dog(490183) B-cell CLL/lymphoma 10
- sheep(101113372) B-cell CLL/lymphoma 10
- naked mole-rat(101712563) B-cell CLL/lymphoma 10
- domestic guinea pig(100729772) B-cell CLL/lymphoma 10
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