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Key Documents

TRUEPEG

Sigma-Aldrich

TrueGel3D Crosslinker

PEG non cell-degradable crosslinker

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About This Item

UNSPSC Code:
12352207
NACRES:
NA.71

shipped in

dry ice

storage temp.

−20°C

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General description

PEG-Link is comprised of polyethylene glycol and thiol (SH) groups at each end. The thiol groups form stable thioether bond with thiol-reactive groups of the polymers (Mal-PVA, Mal-Dextran, SG-PVA and SG-Dextran), which results in stable hydrogel. The matrix metalloproteases secreted by cells cannot cleave PEG crosslinker.

Application

TRUEPEG is used to crosslink PVA and dextran polymers to generate stable hydrogel.

Features and Benefits

Non-MMP degradable.

Components

TRUEPEG contains PEG non cell-degradable crosslinker lyophilized and water.

Caution

Avoid prolong exposure of PEG non cell-degradable crosslinker to air.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3


Certificates of Analysis (COA)

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Articles

TrueGel3D hydrogels kits for 3D cell culture troubleshooting guide

Protocols

TrueGel3D™ is a chemically-defined hydrogel formed by mixing polymers with crosslinkers. This hydrogel permits the encapsulation of cells to put them in a three-dimensional environment to better mimic the native tissue environment.

TrueGel3D™ is chemically defined hydrogel, enables cell growth in 3D environment and mimics native tissue environment. Slow gelation facilitates filling of microchannels or syringes. Find detail protocol of slow gelation for TrueGel3D™ kits

Related Content

An advanced protocol is available for TrueGel 3D kits for 3D cell culture for peptides concentration or stiffness optimisation

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