Skip to Content
Merck
All Photos(2)

Key Documents

SRP0342

Sigma-Aldrich

cKit active human

recombinant, expressed in baculovirus infected Sf9 cells, ≥32% (SDS-PAGE)

Synonym(s):

CD117, KIT, PBT, SCFR, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

Sign Into View Organizational & Contract Pricing


About This Item

CAS Number:
UNSPSC Code:
12352200
NACRES:
NA.32

biological source

human

recombinant

expressed in baculovirus infected Sf9 cells

Assay

≥32% (SDS-PAGE)

form

aqueous solution

mol wt

53.5 kDa

packaging

pkg of 10 μg

technique(s)

activity assay: suitable
inhibition assay: suitable

NCBI accession no.

UniProt accession no.

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... KIT(3815)

General description

Human cKit (D816V) ( GenBank Accession No. NM_000222), amino acids 544-end with N-terminal His-tag, MW=50 kDa, expressed in an Baculovirus infected Sf9 cell expression system.

Application

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

Physical form

Fomulated in 25 mM Tris-HCl, pH 8.0, 138 mM NaCl, 0.05% Tween-20, 3 mM DTT and 10% glycerol.

Pictograms

Health hazardExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Mauro Picardo et al.
The Journal of investigative dermatology, 131(6), 1182-1185 (2011-05-14)
Cutaneous pigmentation is regulated by a complex melanogenic network in which skin cells synthesize growth factors and cytokines. Mutations in genes encoding these regulators modify their expression and/or functionality, leading to altered signaling pathways and contributing to altered skin phenotypes.
Y Yarden et al.
The EMBO journal, 6(11), 3341-3351 (1987-11-01)
Structural features of v-kit, the oncogene of HZ4 feline sarcoma virus, suggested that this gene arose by transduction and truncation of cellular sequences. Complementary DNA cloning of the human proto-oncogene coding for a receptor tyrosine kinase confirmed this possibility: c-kit

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service