SML2591

SCH-39166 hydrobromide

≥98% (HPLC)

• Synonym(s): (-)-trans-6,7,7a,8,9,13b-Hexahydro-3-chloro-2-hydroxy-N-methyl- 5H-benzo[d]naptho-(2,1-b)azepine hydrobromide, (6aS,13bR)-11-Chloro-6,6a,7,8,9,13b-hexahydro-7-methyl-5H-benzo[d]naphth[2,1-b]azepin-12-ol hydrobromide, (6aS-trans)-11-Chloro-6,6a,7,8,9,13b-hexahydro-7-methyl-5H-Benzo[d]naphth[2,1-b]azepin-12-ol hydrobromide, Ecopipam hydrobromide, PSYRX 101 hydrobromide, PSYRX-101 hydrobromide, PSYRX101 hydrobromide, SCH 39166 hydrobromide, SCH39166 hydrobromide
• Empirical Formula (Hill Notation): C₁₉H₂₀ClNO·HBr
• CAS Number: 1227675-51-5
• Molecular Weight: 394.73
• MDL number: MFCD08703109
• UNSPSC Code: 12352200
• NACRES: NA.77

Properties

• Assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C

Description

Biochem/physiol Actions

SCH-39166 (ecopipam) is a high-affinity D_1/D₅ subtype-selective dopamine receptor antagonist (K_i = 1.2 nM/D₁, 2.0 nM/D₅, 980 nM/D₂, 5.52 μM/D₄, 80 nM/5-HT, 731 nM/α_2a). SCH-39166 is widely employed both in cultures and in animal studies in vivo.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H336
• Hazard Classifications: STOT SE 3
• Target Organs: Central nervous system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable