SML1137

ELN484228

≥98% (HPLC)

• Synonym(s): 4′-Fluorobenzenesulfonanilide, N-(4-Fluorophenyl)-benzenesulfonamide, N-(4-Fluorophenyl)benzenesulfonamide, N-(p-Fluorophenyl)benzenesulfonamide, NSC 164389
• Empirical Formula (Hill Notation): C₁₂H₁₀FNO₂S
• CAS Number: 312-63-0
• Molecular Weight: 251.28
• MDL number: MFCD00091019
• UNSPSC Code: 12352202
• PubChem Substance ID: 329825673
• NACRES: NA.77

Properties

• Assay: ≥98% (HPLC)
• form: powder
• storage condition: protect from light
• color: white to beige
• solubility: DMSO: 20 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: O=S(C1=CC=CC=C1)(NC2=CC=C(F)C=C2)=O
• InChI: 1S/C12H10FNO2S/c13-10-6-8-11(9-7-10)14-17(15,16)12-4-2-1-3-5-12/h1-9,14H
• InChI key: AZORQGXJAXEIGC-UHFFFAOYSA-N

Description

Biochem/physiol Actions

ELN484228 is a cell penetrant α-synuclein ligand that rescues of α-synuclein induced disruption of vesicle trafficking and dopaminergic neuronal loss and neurite retraction. ELN484228 reverses a-synuclein induced impairment of phagocytosis and protects dopaminergic neurons against the toxic effects of α-synuclein A53T over-expression.

Features and Benefits

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Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302,H319
• Precautionary Statements: P264 - P270 - P280 - P301 + P312 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable