SAB5702963

Anti-COX2/PTGS2 Antibody, clone 2V7G8, Rabbit Monoclonal

• Synonym(s): COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2
• UNSPSC Code: 12352203
• NACRES: NA.46

Properties

• biological source: rabbit
• Quality Level: 100
• material: colorless
• clone: 2V7G8, monoclonal
• form: liquid
• mol wt: 72 kDa
• species reactivity: mouse, mouse
• concentration: 0.8 mg/mL
• technique(s): immunohistochemistry: 1:50 - 1:200; western blot: 1:500 - 1:2000
• color: colorless
• isotype: IgG
• immunogen sequence: GETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL
• UniProt accession no.: P35354
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... PTGS2(5743)

Description

General description

Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. [provided by RefSeq, Feb 2009]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 505-604 of human COX2/PTGS2 (P35354).

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Application

WB, IHC

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1