SAB5700316

Anti-Phospho-MAX-S11 antibody produced in rabbit

• Synonym(s): MAX, bHLHd4
• UNSPSC Code: 12352203

Properties

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: 11; 12; 15; 17; 18; 9
• species reactivity: human
• concentration: 0.20 mg/ml
• technique(s): immunofluorescence: 1:50-1:200; western blot: 1:500-1:2000
• UniProt accession no.: P61244
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pSer11)
• Gene Information: human ... MAX(4149)

Description

General description

The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants.

Immunogen

A synthetic phosphorylated peptide around S11 of human MAX (NP_002373.3).

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable