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O3129

Sigma-Aldrich

N-Octanoyl-N-methylglucamine

≥97% (GC)

Synonym(s):

N-(D-Glucityl)-N-methyloctanamide, N-Methyl-N-octanoyl-D-glucamine, MEGA-8, OMEGA

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About This Item

Empirical Formula (Hill Notation):
C15H31NO6
CAS Number:
85316-98-9
Molecular Weight:
321.41
Beilstein:
5816747
MDL number:
MFCD00134152
UNSPSC Code:
12352201
PubChem Substance ID:
24897973
NACRES:
NA.25

description

non-ionic

Assay

≥97% (GC)

form

powder

mol wt

321.41 g/mol

color

white

CMC

58 mM (20-25°C)

solubility

water: 50 mg/mL, clear, colorless

SMILES string

CCCCCCCC(=O)N(C)C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

InChI

1S/C15H31NO6/c1-3-4-5-6-7-8-13(20)16(2)9-11(18)14(21)15(22)12(19)10-17/h11-12,14-15,17-19,21-22H,3-10H2,1-2H3/t11-,12+,14+,15+/m0/s1

InChI key

SBWGZAXBCCNRTM-CTHBEMJXSA-N

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Application

N-Octanoyl-N-methylglucamine has been used in a study to assess disordered the N-terminus of PKA. It has also been used in a study to investigate the usefulness of sugar surfactants as solubilizing agents in parenteral formulations.
Non-ionic detergent used for the solubilization of proteins

Biochem/physiol Actions

Water soluble detergent with high solubilising power and non-denaturating properties. Readily removed by dialysis.; Does not interfere with the monitoring of proteins at 280 nm.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Giulio Poli et al.
Frontiers in chemistry, 6, 229-229 (2018-07-05)
Herein we present the algorithm and performance assessment of our newly developed conformer generator iCon that was implemented in LigandScout 4.0. Two data sets of high-quality X-ray structures of drug-like small molecules originating from the Protein Data Bank (200 ligands)
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PLoS genetics, 15(2), e1007934-e1007934 (2019-02-12)
Ovules contain the female gametophytes which are fertilized during pollination to initiate seed development. Thus, the number of ovules that are produced during flower development is an important determinant of seed crop yield and plant fitness. Mutants with pleiotropic effects
Christine Breitenlechner et al.
Biochemistry, 43(24), 7743-7749 (2004-06-16)
Protein kinases comprise the major enzyme family critically involved in signal transduction pathways; posttranslational modifications affect their regulation and determine signaling states. The prototype protein kinase A (PKA) possesses an N-terminal alpha-helix (Helix A) that is atypical for kinases and
Daniel J White et al.
Journal of computational biology : a journal of computational molecular cell biology, 24(9), 874-881 (2017-04-18)
Applying high-throughput sequencing to pathogen discovery is a relatively new field, the objective of which is to find disease-causing agents when little or no background information on disease is available. Key steps in the process are the generation of millions
Meng-Hsien Chuang et al.
Integrative cancer therapies, 16(4), 516-525 (2016-10-05)
JC-001 is a Chinese medicine that has been used to treat liver disease; however, its significance in cancer treatment has not been characterized. In this study, we used an immunocompetent tumor model to characterize the antitumor activity of JC-001. A
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