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N4006

Sigma-Aldrich

Naphthol AS-BI N-acetyl-β-D-glucosaminide

β-hexosaminidase substrate, ≥97% (TLC), powder

Synonym(s):

2-Naphthalenecarboxamide, 3-[[2-(acetylamino)-2-deoxy-β-D-glucopyranosyl]oxy]-7-bromo-N-(2-methoxyphenyl)-, Naphthol AS-BI 2-acetamido-2-deoxy-β-D-glucopyranoside

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About This Item

Empirical Formula (Hill Notation):
C26H27BrN2O8
CAS Number:
3395-37-7
Molecular Weight:
575.41
MDL number:
MFCD00076131
UNSPSC Code:
12352204
PubChem Substance ID:
24897360
NACRES:
NA.83

product name

Naphthol AS-BI N-acetyl-β-D-glucosaminide, β-hexosaminidase substrate

Quality Level

200

Assay

≥97% (TLC)

form

powder

solubility

DMF: 50 mg/mL

storage temp.

−20°C

SMILES string

COc1ccccc1NC(=O)c2cc3cc(Br)ccc3cc2OC4OC(CO)C(O)C(O)C4NC(C)=O

InChI

1S/C26H27BrN2O8/c1-13(31)28-22-24(33)23(32)21(12-30)37-26(22)36-20-11-14-7-8-16(27)9-15(14)10-17(20)25(34)29-18-5-3-4-6-19(18)35-2/h3-11,21-24,26,30,32-33H,12H2,1-2H3,(H,28,31)(H,29,34)

InChI key

DMLKUPXKUQREOC-UHFFFAOYSA-N

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Amelioration of renal impairment is the key to diabetic nephropathy (DN) therapy. The progression of DN is closely related to podocyte dysfunction, but the detailed mechanism has not yet been clarified. The present study aimed to explore the renal impairment
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Aquatic toxicology (Amsterdam, Netherlands), 160, 1-12 (2015-01-09)
Mytilus species are important organisms in marine systems being highly abundant and widely distributed along the coast of Europe and worldwide. They are typically used in biological effects studies and have a suite of biological effects endpoints that are frequently
Oeystein R Brekk et al.
Acta neuropathologica communications, 8(1), 127-127 (2020-08-09)
Sandhoff disease (SD) is a lysosomal storage disease, caused by loss of β-hexosaminidase (HEX) activity resulting in the accumulation of ganglioside GM2. There are shared features between SD and Parkinson's disease (PD). α-synuclein (aSYN) inclusions, the diagnostic hallmark sign of

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