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M1397

Sigma-Aldrich

Anti-Mouse IgG (γ-chain specific) antibody produced in goat

affinity isolated antibody, lyophilized powder

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About This Item

MDL number:
UNSPSC Code:
12352203
NACRES:
NA.46

biological source

goat

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

secondary antibodies

clone

polyclonal

form

lyophilized powder

technique(s)

Ouchterlony double diffusion: suitable

storage temp.

2-8°C

target post-translational modification

unmodified

General description

IgG antibody subtype is the most abundant serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defence of the neonate against infections. Anti-Mouse IgG (γ-chain specific) antibody is specific for γ chain of mouse IgG subclasses.

Immunogen

Purified mouse IgG

Application

Anti-Mouse IgG (γ-chain specific) antibody is suitable for Ouchterlony Double Diffusion. It was used at a concentration of 0.1 μg/ml in a double antibody sandwich ELISA to measure total IgG level in mouse sera.

Physical form

Lyophilized from 0.01 M sodium phosphate, 0.015 M sodium chloride, pH 7.2.

Reconstitution

Reconstitute with 0.135 M sodium chloride.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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H Dumortier et al.
Journal of immunology (Baltimore, Md. : 1950), 165(4), 2297-2305 (2000-08-05)
Autoantibodies directed against spliceosomal heterogeneous nuclear ribonucleoproteins (hnRNPs) are a typical feature of rheumatoid arthritis, systemic lupus erythematosus, and mixed-connective tissue disease. With the aim of investigating a potential pathogenic role of these Abs, we have studied the Ab response
Alexander Astrakhan et al.
Nature immunology, 8(5), 522-531 (2007-04-03)
The cytokine thymic stromal lymphopoietin (TSLP) drives immature B cell development in vitro and may regulate T helper type 2 responses. Here we analyzed the involvement of TSLP in B cell development in vivo with a doxycycline-inducible, keratin 5-driven transgene
Paola Favuzza et al.
Malaria journal, 15, 161-161 (2016-03-17)
The pathogenesis of malaria is primarily associated with blood-stage infection and there is strong evidence that antibodies specific for parasite blood-stage antigens can control parasitaemia. This provides a strong rationale for incorporation of asexual blood-stage antigen components into an effective
Greg A Kirchenbaum et al.
Journal of immunology research, 2017, 5874572-5874572 (2017-03-14)
The domestic ferret (
S Pauliina Turunen et al.
Innate immunity, 21(4), 370-385 (2014-08-20)
Periodontal infections increase the risk of atherosclerotic vascular disease via partly unresolved mechanisms. Of the natural IgM Abs that recognize molecular mimicry on bacterial epitopes and modified lipid and protein structures, IgM directed against oxidized low-density lipoprotein (LDL) is associated

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