G8877
Guanosine 5′-triphosphate sodium salt hydrate
≥95% (HPLC), powder
Synonym(s):
GTP
About This Item
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Quality Level
Assay
≥95% (HPLC)
form
powder
color
white
solubility
H2O: 50 mg/mL
shipped in
dry ice
storage temp.
−20°C
SMILES string
[Na+].[Na+].[Na+].NC1=Nc2c(ncn2[C@@H]3O[C@H](COP(O)(=O)OP([O-])(=O)OP([O-])([O-])=O)[C@@H](O)[C@H]3O)C(=O)N1
InChI
1S/C10H16N5O14P3.3Na/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21;;;/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,11,13,14,18);;;/q;3*+1/p-3/t3-,5-,6-,9-;;;/m1.../s1
InChI key
KZRMTEVIDYXWQW-CYCLDIHTSA-K
Gene Information
human ... HRAS(3265)
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Related Categories
Application
- in the preparation of horseradish peroxidase (HRP)-modified platination reagents
- in whole cell, voltage-clamp recordings
- in in vitro inhibition of transglutaminase (tTG)
Biochem/physiol Actions
Features and Benefits
Preparation Note
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Protocols
HPLC Analysis of GMP, GDP and GTP on SeQuant ZIC-HILIC
ZIC-cHILIC is a densely bonded zwitterionic stationary phase with phosphorylcholine functional groups covalently attached to silica.
Related Content
Cyclic nucleotides, including cyclic AMP (cAMP), cyclic GMP (cGMP) and cyclic ADP-ribose, have been extensively studied as second messengers of intracellular events initiated by activation of GPCRs. cAMP modifies cell function in all eukaryotic cells, principally through the activation of cAMP-dependent protein kinase (PKA), but also through cAMP-gated ion channels and guanine nucleotide exchange factors directly activated by cAMP.
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