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G0777

Sigma-Aldrich

Ginsenoside-Rb1 from Panax ginseng (Korean ginseng) root

triterpenoid saponin, ≥98% (HPLC)

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About This Item

Empirical Formula (Hill Notation):
C54H92O23
CAS Number:
41753-43-9
Molecular Weight:
1109.29
EC Number:
255-532-8
MDL number:
MFCD00133367
UNSPSC Code:
12352201
PubChem Substance ID:
24895025
NACRES:
NA.25

biological source

plant root (Panax ginseng)

Quality Level

200

Assay

≥98% (HPLC)

form

powder

technique(s)

HPLC: suitable

impurities

≤10% water (Karl Fischer)

color

white to yellow cast

mp

186 - 188  °C ((367 - 370 °F ))

solubility

methanol: soluble 9.80-10.20 mg/mL, clear, colorless to faintly yellow

storage temp.

2-8°C

SMILES string

C\C(C)=C\CCC(C)(OC1OC(COC2OC(CO)C(O)C(O)C2O)C(O)C(O)C1O)C3CCC4(C)C3C(O)CC5C6(C)CCC(OC7OC(CO)C(O)C(O)C7OC8OC(CO)C(O)C(O)C8O)C(C)(C)C6CCC45C

InChI

1S/C54H92O23/c1-23(2)10-9-14-54(8,77-48-44(69)40(65)37(62)29(74-48)22-70-46-42(67)38(63)34(59)26(19-55)71-46)24-11-16-53(7)33(24)25(58)18-31-51(5)15-13-32(50(3,4)30(51)12-17-52(31,53)6)75-49-45(41(66)36(61)28(21-57)73-49)76-47-43(68)39(64)35(60)27(20-56)72-47/h10,24-49,55-69H,9,11-22H2,1-8H3/t24-,25+,26+,27+,28+,29+,30-,31+,32-,33-,34+,35+,36+,37+,38-,39-,40-,41-,42+,43+,44+,45+,46+,47-,48-,49-,51-,52+,53+,54-/m0/s1

InChI key

GZYPWOGIYAIIPV-JBDTYSNRSA-N

Application

Ginsenoside-Rb1 from Panax ginseng, a triterpenoid saponin, may be used in ginseng-derived bioactive molecules research to study its mechanisms of action, pharmacokinetics, safety and efficacy as a cardioprotective agent. Ginsenoside-Rb1 may be used to help identify and characterize enzymes with ginsenoside converting activities.

Biochem/physiol Actions

Triterpene saponin found in ginseng.

Other Notes

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Precautionary Statements

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Chiung-Hung Chang et al.
PloS one, 9(8), e105362-e105362 (2014-08-19)
Salmonella, a common zoonotic pathogen, causes gastroenteritis in both humans and animals. Traditional Chinese Medicine (TCM) has been used to improve gastrointestinal dysfunction and to modify the immune response to inflammation for centuries. This study used six herbal plants and
Yuanyang Zhao et al.
Journal of translational medicine, 13, 174-174 (2015-06-03)
Jiangzhi Capsule is an Australian listed patented traditional Chinese medicine and has been used for management of lipid abnormalities over the past 10 years. To obtain a better understanding regarding Jiangzhi Capsule, the present study investigated the effects and underlying
Chun-Ying Liu et al.
Journal of ginseng research, 39(3), 221-229 (2015-07-23)
Minor ginsenosides, those having low content in ginseng, have higher pharmacological activities. To obtain minor ginsenosides, the biotransformation of American ginseng protopanaxadiol (PPD)-ginsenoside was studied using special ginsenosidase type-I from Aspergillus niger g.848. DEAE (diethylaminoethyl)-cellulose and polyacrylamide gel electrophoresis were
Dan-dan Tian et al.
Acta pharmacologica Sinica, 36(5), 627-643 (2015-04-22)
Tanshinol is an important catechol in the antianginal herb Salvia miltiorrhiza roots (Danshen). This study aimed to characterize tanshinol methylation. Metabolites of tanshinol were analyzed by liquid chromatography/mass spectrometry. Metabolism was assessed in vitro with rat and human enzymes. The

Chromatograms

application for HPLC

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