C7956

Coenzyme Q₁

≥95%

• Synonym(s): 2,3-Dimethoxy-5-methyl-6-(3-methyl-2-butenyl)-1,4-benzoquinone, Ubiquinone-1, Ubiquinone-5
• Empirical Formula (Hill Notation): C₁₄H₁₈O₄
• CAS Number: 727-81-1
• Molecular Weight: 250.29
• MDL number: MFCD00274412
• UNSPSC Code: 12352204
• PubChem Substance ID: 24892585
• NACRES: NA.51

Properties

• Assay: ≥95%
• form: liquid
• storage temp.: −20°C
• SMILES string: COC1=C(OC)C(=O)C(C\C=C(\C)C)=C(C)C1=O
• InChI: 1S/C14H18O4/c1-8(2)6-7-10-9(3)11(15)13(17-4)14(18-5)12(10)16/h6H,7H2,1-5H3
• InChI key: SOECUQMRSRVZQQ-UHFFFAOYSA-N

Description

General description

Coenzyme Q (CoQ) is localized to the hydrophobic domain of the phospholipid bilayer of mitochondria, plasma lipoproteins, and other biological membranes. It is a ubiquinone homolog with a short isoprenoid side chain.

Application

Coenzyme Q1 has been used to measure the mitochondrial respiratory chain complex 1 activity.

Biochem/physiol Actions

Coenzyme Q1 (CoQ1) is a 1 isoprenyl group (not naturally occurring) member of a family of ubiquinones that share a quinine chemical group but differ in the number of isoprenyl chemical subunits in their tail. The CoQ compounds are lipid soluble components of cell membranes where they perform multiple functions such as electron and proton transport. The most well studied CoQ compound is CoQ10. CoQ1 is frequently used in comparison studies on the effect of isoprenyl chain length on CoQ functions or distribution and to identify quinone reductases.

Other Notes

Analog of coenzyme Q₁₀ (not naturally occurring)

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves