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A9256

Sigma-Aldrich

L-Aspartic acid

≥98% (HPLC)

Synonym(s):

(S)-(+)-Aminosuccinic acid, (S)-Aminobutanedioic acid

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About This Item

Linear Formula:
HO2CCH2CH(NH2)CO2H
CAS Number:
56-84-8
Molecular Weight:
133.10
Beilstein:
1723530
EC Number:
200-291-6
MDL number:
MFCD00002616
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
24277948
NACRES:
NA.26

product name

L-Aspartic acid, reagent grade, ≥98% (HPLC)

grade

reagent grade

Quality Level

200

Assay

≥98% (HPLC)

form

powder, crystals or chunks

color

white to off-white

mp

>300 °C (dec.) (lit.)

solubility

H2O: 5 mg/mL
0.5 M HCl: 50 mg/mL (with heat)
1 M NaOH: 50 mg/mL

SMILES string

N[C@@H](CC(O)=O)C(O)=O

InChI

1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/t2-/m0/s1

InChI key

CKLJMWTZIZZHCS-REOHCLBHSA-N

Gene Information

human ... CA1(759) , CA2(760)
rat ... Grin2a(24409)

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Application

L-aspartic acid has been used as one of the components of synthetic drop out media for culturing budding yeast. It has also been used to study non-enzymatic gluconeogenesis.

Biochem/physiol Actions

Principal neurotransmitter for fast synaptic excitation.
Aspartic acid is a non-essential amino acid. It is involved in the Urea cycle, Krebs cycle and in DNA metabolism.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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The Healing Nutrients Within: Facts, Findings, and New Research on Amino Acids, 1-504 (2007)
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Bio-protocol, 7(18), 1-24 (2017)
Nonenzymatic gluconeogenesis-like formation of fructose 1,6-bisphosphate in ice.
Messner CB
Proceedings of the National Academy of Sciences of the USA, 114(28), 7403-7407 (2017)
Jorge S Valadas et al.
Neuron, 98(6), 1155-1169 (2018-06-12)
Parkinson's disease patients report disturbed sleep patterns long before motor dysfunction. Here, in parkin and pink1 models, we identify circadian rhythm and sleep pattern defects and map these to specific neuropeptidergic neurons in fly models and in hypothalamic neurons differentiated
Christoph B Messner et al.
Proceedings of the National Academy of Sciences of the United States of America, 114(28), 7403-7407 (2017-06-28)
The evolutionary origins of metabolism, in particular the emergence of the sugar phosphates that constitute glycolysis, the pentose phosphate pathway, and the RNA and DNA backbone, are largely unknown. In cells, a major source of glucose and the large sugar
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