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Key Documents

O8380

Sigma-Aldrich

1-Octanesulfonic acid sodium salt

≥98%

Synonym(s):

Octane-1-sulfonic acid sodium salt, Sodium 1-octanesulfonate, Sodium octane-1-sulfonate, Sodium octanesulfonate

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About This Item

Linear Formula:
C8H17O3SNa
CAS Number:
Molecular Weight:
216.27
EC Number:
MDL number:
UNSPSC Code:
12161900
PubChem Substance ID:
NACRES:
NA.21

biological source

synthetic (oragnic)

Quality Level

description

anionic

Assay

≥98%

form

powder

mol wt

216.27 g/mol

technique(s)

HPLC: suitable

impurities

<2.0% water (Karl Fischer)

mp

300  °C (572 °F)

solubility

9.8 g/L at 20 °C

cation traces

Na: 10.1-11.1 % (w/v) (Anhydrous)

SMILES string

[Na+].CCCCCCCCS([O-])(=O)=O

InChI

1S/C8H18O3S.Na/c1-2-3-4-5-6-7-8-12(9,10)11;/h2-8H2,1H3,(H,9,10,11);/q;+1/p-1

InChI key

HRQDCDQDOPSGBR-UHFFFAOYSA-M

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General description

1-Octanesulfonic acid sodium is an anionic detergent and a surfactant with excellent coupling properties. This versatile molecule finds application as a buffer component, in cell biology, analytical chemistry, and biochemical research.

Application

1-Octanesulfonic acid sodium salt has been used:
  • as a component of 9 parts buffer to determine the concentration of L-Dopa in extracts of seed flour
  • in mobile phase solution to measure dopamine in rats using high-performance liquid chromatography (HPLC) analysis
  • in neurochemistry for the preparation of mobile phase buffer for HPLC analysis.

Ion-pairing reagent for HPLC analysis of peptides and proteins.

Features and Benefits

  • Highly versatile surfactant for your cell biology and biochemical research
  • Suitable for HPLC applications

Other Notes

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Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B

Storage Class Code

8B - Non-combustible corrosive hazardous materials

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Can Zhang et al.
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Paclitaxel (Taxol), PTX) is a promising anti-cancer drug and has been successfully used to treat a wide variety of cancers. Unfortunately, serious clinical side effects are associated with it, which are caused by PTX itself and non-aqueous vehicle containing Cremophor
J G Foulks et al.
Canadian journal of physiology and pharmacology, 63(10), 1327-1334 (1985-10-01)
The potency of various types of alkyl amphipathic (cationic, anionic, and neutral) as well as tertiary amine local anesthetics in impairing the excitability of frog skeletal muscle was markedly enhanced by an increase in temperature from 20 to 30 degrees
H T Jung et al.
Proceedings of the National Academy of Sciences of the United States of America, 98(4), 1353-1357 (2001-02-15)
Equilibrium unilamellar vesicles are stabilized by one of two distinct mechanisms depending on the value of the bending constant. Helfrich undulations ensure that the interbilayer potential is always repulsive when the bending constant, K, is of order k(B)T. When K
W Xie et al.
Biochimica et biophysica acta, 1768(5), 1299-1308 (2007-03-14)
Perfluorooctanesulfonic acid (PFOS) is a persistent environmental pollutant that may cause adverse effects by inhibiting pulmonary surfactant. To gain further insights in this potential mechanism of toxicity, we investigated the interaction of PFOS potassium salt with dipalmitoylphosphatidylcholine (DPPC) - the
Xin Su et al.
Chemical communications (Cambridge, England), 49(26), 2655-2657 (2013-02-26)
We report two CO2-responsive aqueous solutions having switchable viscosity. The solution of sodium octadecyl sulfate and 2-(dimethylamino)ethanol forms viscoelastic worm-like micelles in the presence of CO2 but not in its absence at 60 °C. Another solution of sodium stearate and

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